Viracept


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Noun1.Viracept - a protease inhibitor (trade name Viracept) used in treating HIV usually in combination with other drugs
protease inhibitor, PI - an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
References in periodicals archive ?
Since then I have taken AZT, ddI, d4T, Crixivan, Viracept, Viramune, Bactrim, Megace, and others.
Because I lived in Baltimore, home to Johns Hopkins Hospital, and near to the National Institutes of Health in Bethesda, and because I had good health insurance from my second theater job, I began treating for the disease in 1992, taking whatever drugs (AZT, ddI, d4T, Viracept) coming through the pipeline that my doctor, Janet Horn, suggested.
They include saquinavir (Invirase), ritonavir (Norvir), indinavir (Crixivan) and nelfinavir (Viracept), among others.
The assessment affects nineteen centrally authorised medicines as well as various medicines that have been nationally authorised: Avastin, Bondenza, Bondronat, Bonviva, Cellcept, Fuzeon, Herceptin, Invirase, Mabthera, Mircera, Neorecormon, Pegasys, Roactemra, Tamiflu, Tarceva, Viracept, Xeloda, Xenical and Zelboraf.
The HIV drug was approved by the US Food and Drug Administration in 1997, and is sold under the brand name Viracept. It works by inhibiting HIV proteases, or protein-cleaving enzymes, that the virus needs to reproduce.
Those with the strongest inhibitory effects were the asthma drug montelukast (Singulair), and the protease inhibitors nelfinavir (Viracept) and ritonavir (Norvir), which were associated with 90%-100% inhibition of 17P.
Four people were taking two drugs with strong warnings about their combination--3 taking a PI plus Flonase (fluticasone, for nasal allergies or difficulty breathing) and 1 taking the PI Viracept (nelfinavir) and a stomach acid controller.
If a trial had been launched in '97, he notes, "we would just be getting final results, and we would have a lot of information on d4T, Crixivan and Viracept regimens [stavudine (Zerit), indinavir, and nelfinavir].
LPV + RTV, 2 tablets bd po Nelfinavir (NLF, AUC and plasma concen- Take with meals or a Viracept) 750 mg trations increase after light snack that td or 1 250 mg bd a meal.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase Fusion inhibitors (FI) Enfuvirtide Fuzeon
issued a letter * warning health-care providers about the use of Viracept[R] (nelfinavir) (Pfizer, Inc., New York, New York), another protease inhibitor, because the Viracept manufactured in Europe contained high levels of ethyl methane mesylate (EMS).