osteogenesis imperfecta(redirected from Vrolik disease)
Also found in: Thesaurus, Medical, Encyclopedia.
A genetic disease marked by abnormal fragility and plasticity of bone, with recurring fractures resulting from minimal trauma.
[New Latin : osteogenesis + Latin imperfecta, feminine of imperfectus, incomplete.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
(Pathology) a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities. Also called: brittle bone syndrome
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Switch to new thesaurus
|Noun||1.||osteogenesis imperfecta - autosomal dominant disorder of connective tissue characterized by brittle bones that fracture easily|
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
osteogenesis imperfectan osteogénesis imperfecta
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.