Waldenstrom's macroglobulinemia

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Waldenstrom's macroglobulinemia

n. Waldenstrom, macroglobulinemia de, síndrome hemorrágico con manifestaciones de anemia y adenomegalia.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
Calquence is being developed for the treatment of multiple B-cell blood cancers including CLL, MCL, diffuse large B-cell lymphoma, Waldenstrom macroglobulinemia, follicular lymphoma, and multiple myeloma and other hematologic malignancies.
This will likely prove definitive in the head-to-head Phase III trials to read out later in the year in Waldenstrom macroglobulinemia, Van Buren tells investors in a research note titled "The BeiGene Global Portfolio Development Strategy Remains On Track." Further, the analyst finds the combo's activity in chronic lymphocytic leukemia/small lymphocytic lymphoma and Hodgkin's lymphoma "promising."
Summary: Waldenstrom macroglobulinemia is a rare cancer and is characterized by high level of immunoglobulin M (IgM) in the serum, which leads to increased serum viscosity, and presence of a lymphoplasmacytic infiltrate in the bone marrow.
Janssen Research & Development, a subsidiary of Johnson & Johnson, has indicated improved progression-free survival in patients with Waldenstrom macroglobulinemia (WM), a form of non-Hodgkin's lymphoma, when administered with a combination of Imbruvica (ibrutinib) and rituximab (Rituxan) in its Phase three iNNOVATE (PCYC-1127) study, it was reported yesterday.
On day 3 after his Mohs procedure, one 73-year-old man taking ibrutinib for Waldenstrom macroglobulinemia developed extensive bilateral periorbital ecchymosis that extended down to his upper chest.
In studies examining genetic structures of families with CLL, it was found that the members of these families had many other lymphoproliferative disorders (Hodgkin and non-Hodgkin lymphoma, Waldenstrom macroglobulinemia, MBL) in addition to CLL (4).
He had a history of Waldenstrom macroglobulinemia last treated 10 months ago, chronic HBV infection, chronic obstructive pulmonary disease, hypertension, and benign prostate hyperplasia.
Ibrutinib, a selective Bruton's tyrosine kinase inhibitor, was approved initially in November 2013 by the US Food and Drug Administration for the treatment of mantle cell lymphoma and in February 2014 for B-cell chronic lymphocytic leukaemia, and later on also for Waldenstrom macroglobulinemia, all after first-line treatment [1].
Gertz, "Waldenstrom macroglobulinemia: 2017 update on diagnosis, risk stratification, and management," American Journal of Hematology, vol.
Likewise, in the same study there were some limited associations with diffuse large B-cell lymphoma, hairy cell leukemia, splenic B-cell marginal zone lymphoma, and Waldenstrom macroglobulinemia. In our case, it led to the diagnosis of a rare parotid follicular lymphoma associated with Warthin tumor, an unusual coexistence, with 23 previous cases reported.
Waldenstrom macroglobulinemia. Development of diagnostic criteria and identification of prognostic factors.