Yamabe et al., "Mutation and haplotype analyses of the Werner's syndrome
gene based on its genomic structure: Genetic epidemiology in the Japanese population," Human Genetics, vol.
Differential diagnoses are other ageing syndromes like Werner's syndrome
(adult progeria), Cockyane's syndrome, Acrogeria, and Rothmund-Thomson syndrome which can be differentiated by their clinical features.
They includes "Dreaming Water," the life of a woman suffering from Werner's syndrome
, which ages a person twice as fast as normal; and the inhabitants of a leper colony in "The Samurai's Garden."
INTRODUCTION: Werner's syndrome
is a progeroid syndrome.
is a rare inherited disorder characterized by short stature, sclerosed skin, cataract and premature aging of the face.
Unlike most other "accelerated aging diseases" (such as Werner's syndrome
, Cockayne's syndrome, or xeroderma pigmentosum), progeria is not caused by defective DNA repair.
Researchers at the Centre de Recherche en Cancerologie in Quebec said vitamin C reversed accelerated aging in a mouse model of Werner's syndrome
Mutation in the gene WRN is responsible for Werner's Syndrome
, which causes people to age rapidly.
Investigators have found that people who have Werner's syndrome
(WS), a rare disease with several features of premature aging, have a defect in one of their helicases.
Cate is caring for her 34-year-old daughter Hana, who is suffering from Werner's syndrome
, a disease in which the person ages prematurely.
The baby could develop Werner's Syndrome
, which leads to massive ageing and can kill before victims before they are 50.