In 2018, 39 laboratory-confirmed human cases of West Nile virus
and 40 positive mosquito tests were reported to Toronto Public Health.
West Nile virus
neuroinvasive disease (WNVND) was suspected by the detection of WNV IgM by the enzyme-linked immunosorbent assay (ELISA) in both CSF and serum specimens and by a plaque reduction neutralization test (PRNT90) serum titre of 40 for the WNV-specific antibody in the acute serum sample.
This is peak time for West Nile virus
activity and will continue until the first frost.
The announcement added that around 1 in 150 people, or less than 1 per cent of those infected with the West Nile Virus
, will develop a serious form of the disease, affecting the central nervous system, or causing meningitis, encephalitis or acute paralysis.
Signs of West Nile virus
recently appeared in Carson, Signal Hill, Northridge and Reseda in Los Angeles, according to the Greater Los Angeles County Vector Control District.
There have 10 West Nile Virus
human cases reported in California in 2019.
This report provides comprehensive information on the therapeutic development for West Nile Virus
Infections, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
The therapeutics, known as monoclonal antibodies (MAbs) and their derivatives, were shown to neutralize and protect mice against a lethal dose challenge of West Nile virus
-- even as late as 4 days after the initial infection.
Besides Alaska and Hawaii, which have never reported a case of West Nile virus
, Oregon was the only state with no cases of neuroinvasive disease last year.
According to the Dallas County Department of Health and Human Services as of mid-August, 11 residents had died due to West Nile virus
and a total of 230 human cases had been identified.
However, in 2012 there have been more reported cases of West Nile virus
neuroinvasive disease to date than on the same date in any year since 2004, with most of the activity being concentrated in Texas, Oklahoma, and Mississippi, according to Dr.
GIS expert Gonzalo Vazquez-Prokopec of Emory University in Atlanta conducted a spatial analysis for southeastern Atlanta that integrated the locations of so-called combined sewer overflow (CSO) systems--which channel wastewater to treatment plants--and any associated streams with six years worth of data on mosquito abundance and West Nile virus
infections in mosquitoes, humans, bluejays and crows (these birds, which show high West Nile virus
mortality, are used as sentinels for the disease).