What's wrong?

Also found in: Idioms.
What's wrong  
Collins Multilingual Translator © HarperCollins Publishers 2009
References in classic literature ?
"What's wrong?" said Harvey, surprised and a little angry.
"What's wrong?" asked the animal, slightly turning his wooden head to look at the party with one eye, which was a knot of wood.
What's wrong? This has happened to me in the last five half-marathons I've run.