agammaglobulinemia

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Related to X-linked agammaglobulinemia: Bruton's disease, congenital agammaglobulinemia

a·gam·ma·glob·u·lin·e·mi·a

 (ā-găm′ə-glŏb′yə-lə-nē′mē-ə)
n.
A congenital or acquired deficiency of gamma globulins in the blood.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.agammaglobulinemia - a rare immunological disorder characterized by the virtual absence of gamma globulin in the blood and consequent susceptibility to infectionagammaglobulinemia - a rare immunological disorder characterized by the virtual absence of gamma globulin in the blood and consequent susceptibility to infection
immunodeficiency - immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

a·gam·ma·glob·u·lin·e·mi·a

n. agammaglobulinemia, deficiencia de gamma globulina en la sangre.
English-Spanish Medical Dictionary © Farlex 2012

agammaglobulinemia

n agammaglobulinemia
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
X-linked agammaglobulinemia (XLA) / hypogammaglobulinemia, also known as Bruton's agammaglobulinemia is a prototype of humoral immunodeficiency first described by Bruton in 1952.1 It is an uncommon congenital disease and is the major primary immunodeficiency recognised in childhood.
Gottfried, "Gastrointestinal pathology in patients with common variable immunodeficiency and X-linked agammaglobulinemia," The American Journal of Surgical Pathology, vol.
For other primary immunodeficiencies provided by the reader, such as the case of X-linked agammaglobulinemia, this is a congenital disease that affects males and involves B lymphocytes and plasma cells, which are not the primary immune line in tuberculosis (7), nor does it correspond to our case.
Congenital immune deficiencies including complement deficiencies, phagocyte dysfunctions, cell receptor and signal transmission disorders, X-linked agammaglobulinemia which leads to antibody production failure, variable immune deficiencies, severe combined immune deficiency syndrome, complete Di George syndrome, Wiskott-Aldrich syndrome, adaptive immune deficiencies including ataxia-telangiectasia are very important causes of infections, morbidities and mortality.
Once the Btk-dependent signal transduction pathway is inactivated, B cells remain at the pre-B-cells stage leading to X-linked agammaglobulinemia (XLA) in humans, which is one of the most frequently inherited immunodeficient disorders in human, and X-linked immunodeficiency (Xid) in mice [5-8].
Previously, scientists have always thought that BTK is important primarily in antibody production due to observations made of an inherited genetic disorder in humans called X-linked Agammaglobulinemia (XLA).
Octagam is indicated for treatment of primary humoral immunodeficiency (such as congenital agammaglobulinemia), common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.
Clinical, immunological and molecular characteristics of 37 Iranian patients with X-linked agammaglobulinemia. Int Arch Allergy Immunol 2006; 141:408-14.

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