| Noun | 1. | Sao Thome e Principe - island nation in the South Atlantic off the west coast of Africa; achieved independence from Portugal in 1975; has enormous offshore oil reserves Democratic Republic of Sao Tome and Principe, Sao Tome and Principe, Sao Tome e Principe, St. Thomas and Principe Sao Tome - capital of Sao Tome and Principe Principe - an island in the Gulf of Guinea that is part of Sao Tome and Principe Atlantic, Atlantic Ocean - the 2nd largest ocean; separates North and South America on the west from Europe and Africa on the east |