artificial chromosome

A large sequence of DNA, such as a human artificial chromosome or a bacterial artificial chromosome, that is constructed in a laboratory to function like a chromosome or inserted into a cell to be replicated and expressed. Artificial chromosomes have been used in gene mapping and in modeling genetic diseases.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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