| Noun | 1. | clot buster - a kind of pharmaceutical that can break up clots blocking the flow of blood to the heart muscle pharmaceutic, pharmaceutical - drug or medicine that is prepared or dispensed in pharmacies and used in medical treatment Activase, tissue plasminogen activator - a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction |