Noun | 1. | malignant anaemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12) megaloblastic anaemia, megaloblastic anemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia metaplastic anaemia, metaplastic anemia - pernicious anemia in which the various formed elements in the blood are changed |