thalassemia

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Related to a-thalassemia: Alpha Thalassemia, Thalassaemia minor

thal·as·se·mi·a

 (thăl′ə-sē′mē-ə)
n.
An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule. Also called Mediterranean anemia.

[Greek thalassa, sea + -emia.]

thal′as·se′mic adj.

thal•as•se•mi•a

(ˌθæl əˈsi mi ə)

n.
a hereditary anemia marked by the abnormal production of hemoglobin, occurring chiefly in people of Mediterranean origin.
[1932; < Greek thálass(a) sea (alluding to the Mediterranean Sea) + -emia]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thalassemia - an inherited form of anemia caused by faulty synthesis of hemoglobin
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
hypochromic anaemia, hypochromic anemia - anemia characterized by a decrease in the concentration of corpuscular hemoglobin
Cooley's anaemia, Cooley's anemia, thalassaemia major, thalassemia major - a fatal form of homozygous thalassemia (inherited from both parents) in which there is no hemoglobin; skeletal deformations; heart and spleen and liver enlarged
Translations

thal·as·se·mi·a

, thalassanemia
n. talasemia, grupo de diferentes tipos de anemia hemolítica hereditaria encontrada en poblaciones de la región mediterránea y sureste de Asia;
major ______ mayor;
minor ______ menor.

thalassemia

n talasemia
References in periodicals archive ?
Immunologic Abnormalities in a-Thalassemia. Journal of Blood Disorders Transfusion.; 5(7):1-5 (2014).
The patients divided into two groups, the first group included forty eight patients with [beta]-thalassemia major where the number of the female was 23 and the number of the males was 25, the second group included twenty two patients with a-thalassemia where the number of the females was 14 and the number of the males was 8.
Among all patients, [beta]-thalassaemia type major was considered as inclusion criteria, whereas patients with a-thalassemia type minor/major or patients having [beta]-thalassemia type minor were excluded.
We here present a woman with TI a-thalassemia (hemoglobinopathy H), whose pregnancy was complicated with portal vein thrombosis and partial HELLP.
The molecular basis of a-thalassemia. Cold Spring Harb Perspect Med 2013;3(l):a011718.
Francis Borgio et al., "Spectrum of a-thalassemia mutations in transfusion-dependent fithalassemia patients from the eastern province of Saudi Arabia," Hemoglobin, vol.
Thalassemia is an inherited single gene (b-thalassemia) or multiple genes(a-thalassemia) recessive, autosomal blood disease, where hemoglobin is totally absent or partially produced.1,2,3 It is very common in Mediterranean region.4 Hemoglobin is composed of four protein chains, two a-globin chains and two b-globin chains arranged in a hetro-tetramer.5 Patient suffering from thalassemia defects occur either in a or b-globin chain which produced abnormal red blood cells.2
Singer, "Variable clinical phenotypes of a-thalassemia syndromes," TheScientificWorldJournal, vol.
YSSXG Can Promote the Balance of Globin Chain Ratio of Patients with a-Thalassemia and [beta]-Thalassemia Disease.
Some a-thalassemia testing was performed at the Emory Molecular Genetics Laboratory with use of both Southern blot and PCR analysis.