and placenta praevia) where a CS was done (N = 363), the haemorrhage CFR equates to 5.
In pregnant women this can be fatal especially when associated with conditions like preeclampsia (hypertension in pregnancy); oedema (fluid retention in the body); abruptio placentae
(separation of the placenta from the uterus; IUGR (Intrauterine Growth Restriction or poor growth of a baby); gestational diabetes; and pre-term babies.
Related morbidities included obstructed labour, previous CS, abruptio placentae
and placenta praevia.
The major conditions causing obstetric haemorrhage in South Africa during 2005-2007 were abruptio placentae
In general, women with mild disease developing at 38 weeks' gestation or later should undergo induction of labor because these women are at a slightly increased risk for abruptio placentae
and progression to severe disease.
The results showed women with abruptio placentae
were carriers of factor V Leiden in 15.
Pregnancy-related syndromes such as pre-eclampsia, HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets), or DIC (disseminated intravascular coagulation) caused by abruptio placentae
are serious conditions requiring active intervention.
The association of inherited and acquired thrombophilias (which predispose to thrombotic vascular occlusions) with the risk of eclampsia, abruptio placentae
, intrauterine growth restriction (IUGR), and stillbirth has been the object of many studies in the last few years (1).
Maternal toxicities include spontaneous abortions, premature labor and delivery, premature rupture of membranes, placenta previa, and abruptio placentae
, umbilical cord prolapse) (Piper, Mitchel, Snowden, et al.
Placental conditions that have been associated with chorangiosis include umbilical cord anomalies, single umbilical artery, abruptio placentae
, placenta previa, chorangioma, amnion nodosum, and villitis (rubella virus, cytomegalovirus, syphilis, and Bartonella sp are known to infect and induce proliferation of the endothelial cells).
Asphyxia-related causes accounted for 34% of stillbirths, with 63% of asphyxia deaths classified as abruptio placentae