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A substance, C7H17NO3, that is derived from choline and is released at the ends of nerve fibers in the somatic and parasympathetic nervous systems, where it mediates the transmission of nerve impulses.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌæsɪtaɪlˈkəʊliːn; -lɪn)
(Biochemistry) a chemical substance secreted at the ends of many nerve fibres, esp in the autonomic nervous system, and responsible for the transmission of nervous impulses. Formula: CH3CO2(CH2)2N(CH3)3+
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(əˌsit lˈkoʊ lin, əˌsɛt-)

a short-acting neurotransmitter, widely distributed in the body, that functions as a nervous system stimulant, a vasodilator, and a cardiac depressant.
Abbr.: ACh
a•ce`tyl•cho•lin′ic (-ˈlɪn ɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.


A neurotransmitter that triggers activity by muscles or secretory glands.
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.acetylcholine - a neurotransmitter that is a derivative of cholineacetylcholine - a neurotransmitter that is a derivative of choline; released at the ends of nerve fibers in the somatic and parasympathetic nervous systems
neurotransmitter - a neurochemical that transmits nerve impulses across a synapse
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References in periodicals archive ?
This decrease in acetylcholine is responsible for many age-related deficits, including poor memory and the inability to pay attention to tasks.
This is associated with increased striatal acetylcholine levels, which contributes to the development of the motor signs typically associated to Parkinson's disease.
People with Alzheimer's typically have low levels of acetylcholine, and previous research has also found that blocking acetylcholine receptors interferes with memory and the learning process.
Going a little further with an acetylcholine challenge in the cath lab will usually uncover microvascular or vasospastic heart problems, and this can lead to appropriate treatment.
Acetylcholine also plays critical roles elsewhere in the body, such as regulating insulin secretion in the pancreas and in controlling stress and blood pressure.
Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle endplate.
The regional distribution of VAChT situated at presynaptic cholinergic nerve terminals is similar to that of acetylcholine receptors situated at the postsynapses of cholinergic nerve terminals.
Agonists (acetylcholine, histamine) and their appropriate antagonists (atropine, H1 blocker-pheniramine maleate) were used to evaluate the cholinergic and histaminergic mechanisms.
As we age, acetylcholine levels in the brain naturally decrease, but Alzheimer's causes a dramatic multiplier effect that takes us from being forgetful to a different level, says Dr.
While there is no blood test to determine low levels of acetylcholine, there are signs: