acetylcholinesterase


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Related to acetylcholinesterase: Acetylcholinesterase inhibitors

a·ce·tyl·cho·li·nes·ter·ase

 (ə-sēt′l-kō′lə-nĕs′tə-rās′, -rāz′)
n.
An enzyme in the blood and in certain tissues that catalyzes the hydrolysis of acetylcholine.

acetylcholinesterase

(əˈsiːtaɪlˌkəʊliːnˈɛstərˌeɪz; ˈæsɪtaɪl-)
n
(Biochemistry) an enzyme in nerve cells that is responsible for the destruction of acetylcholine and thus for switching off excitation of the nerve

a•ce•tyl•cho•lin•es•ter•ase

(əˌsit lˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, əˌsɛt-, ˌæs ɪ tl-)

n.
an enzyme that counteracts the effects of acetylcholine by hydrolyzing it to choline and acetate.
[1945–50]
References in periodicals archive ?
sup][1],[2] Cholinesterase can be divided into two categories: acetylcholinesterase (AChE) and pseudocholinesterase.
S Rangappa, Active Site Directed Docking Studies: Synthesis and Pharmacological Evaluation of Cis-2, 6-Dimethyl Piperidine Sulfonamides as Inhibitors of Acetylcholinesterase.
Effect of concentrations (mg/L=ppm) of triazophos on acetylcholinesterase (AChE) and butyrylcholinestase (BuChE) activities (umol/min/g protein) of different organs of Catla catla, Labeo rohita and Cirrhinus mrigala.
Are soluble and membrane-bound rat brain acetylcholinesterase different Neurochem.
In this work we seek the possibility of using two enzymes GST and acetylcholinesterase as biomarkers of toxicity with a systemic fungicide ARTEA 330EC in G.
Four Phase II studies of SB742457 in subjects with mild to moderate Alzheimer's disease have been completed, including three monotherapy studies and one adjunctive therapy study in patients already taking an acetylcholinesterase inhibitor, Aricept (donepezil hydrochloride).
acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) has widely been used as biomarkers to evaluate the noxious effects of pesticides i.
7-point improvement in response to the acetylcholinesterase inhibitor.
Huperzine A, a Lycopodium alkaloid produced by Chinese folk herb Huperzia serrata (Lycopodiaceae), has been shown to be a promising agent for the treatment of Alzheimer's disease due to its potent acetylcholinesterase (AChE) activity, as well its efficacy in the treatment of memory of aged patients.
ATCh is an analog of the natural substrate acetylcholine and has been considered a general substrate for ChEs; A(beta)MTCh is a selective substrate for acetylcholinesterase (AChE); PTCh and BTCh are both hydrolyzed by all ChE forms at considerably different rates, but preferably by vertebrate butyrylcho-linesterase (BChE).
Some areas examined include selective serotonin agonists for the acute management of migraine, dual inhibitors of acetylcholinesterase and serotonin transporter targeting potential agents for Alzheimer's disease, and applying control system modeling to understand how genetic variation influences serotonin function and behavior.

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