Idas modiolaeformis specimens display both male and female acini
simultaneously, although all specimens except one displayed only male or female gametes.
In previous studies, Furuta and collaborators have shown that conditioned-medium, taken from normal mammary epithelial cells while in the process of forming acini
in a 3D lamin-rich extracellular matrix culture, can revert the malignant phenotype of breast cancer cells so that they behave as if they were normal breast cells.
AQP-5 appeared mainly at the apical membrane of mucous glands, basolateral membrane and basal membrane of serous acini
. There was intense staining in the intercalated duct, striated duct, and secretory duct of the labial gland (Fig.
The mammary gland contained numerous small acini
with small amounts of milk in the acini
Hartmann, head of the Mayo Clinic's benign breast disease study team, said that in order to standardize assessment of lobular involution and make it faster and more clinically practical, she and her colleagues have developed a quantitative involution measure based upon computerized calculation of lobular area and the number of acini
per lobular unit.
(1) The characteristic histological features are those of a stroma-poor cellular tumour composed of sheets and small glands (acini
) comprising polygonal atypical cells with prominent nucleoli.
Experiments show that 5000 cells/ chamber of human mammary epithelial cell lines (MCF10A) in chamber slide is optimal for the 3D formation of acini
morphology or mammosphere during 20 days.
The prostatic acini
affected by PIN showed a remarkable enlargement of the epithelial layer with pseudostratification and crowding of the nuclei in comparison with normal acini
Whereas early work had predominantly focused on the effects of alcohol on the muscle at the surface of the first part of the small intestine (i.e., duodenum), which controls secretions from the liver, pancreas, and gallbladder into the duodenum (i.e., the sphincter of Oddi), and on the pancreatic ducts (see Figure 1), attention has shifted over the past decade to the influence of alcohol on the clusters of secretory cells (i.e., acini
) that produce pancreatic juice containing digestive enzymes.
The bulk of pancreatic tissue is made up of grapelike clusters of cells (acini
), which produce potent, acidic digestive enzymes and secrete them through ducts into the duodenum.
These results indicate that the pancreatic acini
are target tissues for dioxin and certain dioxin-like compounds.
For spermatogenesis, cells were identified and counted if they touched the X axis of an eyepiece reticule that was moved across the approximate center of 10 acini
(i.e., epithelial sacs within the visceral mass where gametogenesis occurs) per male specimen using a light microscope and 1000x magnification.