The most common multifocal malignancy is acinic
while malignant tumours include mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic
cell carcinoma etc.
Considerations include focal presentation of Sjogren syndrome, lymphoepithelial cysts, first branchial cleft cyst, Warthin's tumor, acinic
cell carcinoma, mucoepidermoid carcinoma, salivary duct carcinoma, and metastatic thyroid papillary carcinoma.
Non-sebaceous lymphadenoma of the salivary gland with serous acinic
cell differentiation, a first case report in the literature.
Ultrasound-guided biopsy was then performed, yielding a diagnosis of parotid acinic
Pleomorphic adenoma, low-grade mucoepidermoid carcinoma, acinic
cell carcinoma, myoepithelial carcinoma low-grade cribriform cystadenocarcinoma, oncocytic carcinoma and salivary duct carcinoma.
(1) Intraosseous acinic
cell carcinoma (ACC) is extremely rare and only 8 cases have been reported so far in English literature.
Both histopathological examination of the incisional biopsy and total surgical of the mass revealed acinic
cell carcinoma of the minor salivary gland; however, they associated the lesion with orbital metastasis of PTC after the histopathological analysis showed the diagnosis of PTC from thyroidectomy specimen.
The accompanying malignant lesions reported in literature are acinic
cell carcinoma and squamous cell carcinoma .
Histology showed monomorphous cells with serous-type clear cell cytoplasm, hyperchromatic nuclei, and partially acinus cell-like growth pattern of the parotid gland resembling acinic
Other lesions described to show oncocytes include both benign and malignant tumours like oncocytic/oncocytoid variants of cystadenoma, myoepithelioma, acinic
cell carcinoma, salivary duct carcinoma, and metastatic renal cell carcinoma .
Some of these lesions are primary laryngeal adenocarcinomas, metastatic adenocarcinoma, salivary glandular tumours like acinic
cell carcinoma, mucoepidermoid carcinoma or adenoid cystic carcinoma of the larynx.