aconitine


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aconitine

(əˈkɒnɪˌtaɪn)
n
(Chemistry) a poison extracted from aconite
Translations
aconitine
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References in periodicals archive ?
It also said that "no therapeutic role in modern western medicine" has been found for Aconitine and its related alkaloids that are known to be "cardiotoxins.
Chemical constituents: The alkaloids, aconitine, atisine, heterophyllisine, histisine occur in all parts of the plant, especially the root and seeds.
sup][1],[5],[6] The results confirmed the significant preventive and therapeutic efficacy of Wenxin Granule on arrhythmias induced by aconitine, barium chloride, and epinephrine.
The plant's toxin is aconitine, which slows the heart until it and respiratory system are both paralysed.
Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes.
Addition of 1 [micro],M aconitine produced inhibitory responses on the colonic spontaneous contractions in the first 2 min, while after the third minute, the spontaneous contractions tended to recover and were intensified.
It appears that voltage-gated sodium channels are the target of many natural neurotoxins that include batrachotoxin as well as tetrodotoxin (TTX), saxitoxin (STX), conus toxins, scorpion toxins and aconitine.
Also known as wolfbane, this contains the alkaloid aconitine, which is a very powerful poison (see Figure 21-13).
Other herbs may be toxic because of possible contaminants: the Chinese herbs caowu and chuanwu used for the management of rheumatism, arthritis, bruises, and fractures may contain highly toxic potentially fatal alkaloids such as aconitine.
Furthermore, this medicinal reservoir has repeatedly contributed drugs such as ephedrine and aconitine to modern medicine in the last century.
ACONITINE - This poison is extracted from the roots of a very common plant which can be found in most garden stores.