Proposed theories for the cause of NAE describe alterations in some metabolic factor, many of which are seen in other necrolytic erythemas, including necrolytic migratory erythema, pellagra, essential fatty acid and biotin deficiency, and acrodermatitis
Since 1999, we have regularly isolated Borrelia burgdorferi sensu lato from skin biopsy specimens of erythema migrans and acrodermatitis
chronica atrophicans taken from patients at the Center for Tick-borne Diseases, Budapest, Hungary.
Erythema migrans and acrodermatitis
chronica atrophicans were observed in 19.5%, and arthritis in 9.3%, reported Dr.
Where palmoplantar pustulosis is a disease of middle life, acrodermatitis
continua of Hallopeau is seen commonly in children.
The differential diagnosis includes acrodermatitis
enteropathica, essential fatty acid deficiency, annular chronic lupus erythematosus, adverse drug reactions, contact dermatitis, and various vitamin deficiencies.
Etiology of the acrodermatitis
chronica atrophicans lesion in Lyme disease.
(3) This may appear to be eczema-like, lichenoid in appearance, or mimicking Gianotti-Crosti syndrome (papular acrodermatitis
In the skin, the well-established forms include erythema chronicum migrans in the early stage of infection and irreversible degenerative acrodermatitis
chronica atrophicans much later.
chronica atrophi- cans, Lyme arthritis, neuro-borreliosis B.
In contrast, infants with acrodermatitis
enteropathica, the inherited form of zinc deficiency, are fine early on while breast feeding because the zinc in breast milk has good bioavailability.
They are unilateral laterothoracic exanthem, acute generalized exanthematous pustulosis, papular acrodermatitis
of childhood, eruptive pseudoangiomatosis, and papular-purpuric gloves and socks syndrome.
Only three cases of acrodermatitis
chronica atrophicans were reported, and cardiac involvement was reported in only five cases.