It has been extensively used in teething powder for children and is now suspected to be the cause of acrodynia
also known as the "pink disease".
In the hospital, he developed a maculopapular rash, acrodynia
(painful, pink discoloration of the hands and feet), tachycardia, hypertension, weakness, sweating, excessive salivation, and altered mental status.
or Erythredema (Swift's Disease): A Pathologic Study of Two Necropsy Cases by Aldred Scott Warthin, PhD, MD, Ann Arbor
or "pink disease" was once a common and sometimes fatal disease in infants before mercury was removed from teething powders, diaper rinses, and laxatives.
Dermal manifestations of mercury vapor exposure may include an erythematous, pruritic rash or acrodynia
(a rare, nonallergic hypersensitivity reaction seen in some children).
Prepubertal periodontitis is usually associated with underlying medical conditions, including but not limited to neutropenia, hypophosphatasia, papillon lefevre syndrome, and acrodynia
In its inorganic form, mercury can cause kidney damage, increased blood pressure, digestive tract problems and impact embryonic development as well as cause a disorder called acrodynia
, a rare condition that causes rapid alveolar bone loss, premature loss of teeth, hair loss and fatigue has also been discounted as a possible cause on the basis that there is no history of mercury poisoning.
Topical exposures have also been known to cause acrodynia
The acute exposure to elemental Hg vapors can cause "pink disease" or acrodynia
When mercury levels in urine are >40 [micro]g/l, symptoms such as fever, tremors, mood swings, insomnia and acrodynia
(pink disease in children) may develop; at levels >60 [micro]g/l, additional respiratory symptoms may develop.