acromegalic

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Related to acromegalic: acromegalic gigantism

ac·ro·meg·a·ly

(ăk′rō-mĕg′ə-lē)

A chronic disorder caused by overproduction of human growth hormone usually by the pituitary gland, characterized by enlargement of the bones of the extremities and the skull and often by the development of complications such as diabetes, hypertension, and osteoarthritis.

[French acromégalie : Greek akron, top, extremity (from neuter of akros, extreme; see acro-) + Greek megas, megal-, big; see meg- in Indo-European roots.]

ac′ro·me·gal′ic (-mĭ-găl′ĭk) adj. & n.

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Adj.

acromegalic - marked or affected by enlargement or hypertrophy of the extremities or the face; "a protruding acromegalic jaw"

unshapely - not well-proportioned and pleasing in shape; "a stout unshapely woman"

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Other complaints were decreased level of consciousness, decreased vision, vomiting, hearing loss, acromegalic features, numbness, proptosis, cerebrospinal fluid (CSF) rhinorrhoea, altered behaviour, ataxia, blindness, dysphagia, oculomotor nerve palsy, diplopia, vertigo, monoplegia, post-auricular discharge and tinnitus.

Short term outcomes following surgery in brain tumours sans neuronavigation

An SSTR5 mutation in tumor tissue was reported in one acromegalic patient who was resistant to SST analog treatment, which implies a role for SSTR5 in predicting response.

Short-term Preoperative Octreotide for Thyrotropin-secreting Pituitary Adenoma

Early postoperative indicators of late outcome in acromegalic patients.

Decrease of Serum IGF-I following Transsphenoidal Pituitary Surgery for Acromegaly

14] showed that significant increase in GH level in acromegalic patients group compared to control group.

Total antioxidant activity and insulin resistance in Iraqi male patients with active Acromegaly: a case control study

Control of tumor size and disease activity during cotreatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient.

Preparation and characterization of an antibody antagonist that targets the porcine growth hormone receptor

The aim of this study was to investigate association between the frequencies of LEP and LEPR gene polymorphisms and subclinical atherosclerosis in acromegalic patients.

Leptin receptor gene polymorphism may affect subclinical atherosclerosis in patients with acromegaly

Acromegalic patients have a deficient activation of brain areas associated with memory, in this case, the temporal and prefrontal region.

Impaired neurocognitive functioning in acromegaly--case report

Difficult intubation in acromegalic patients: incidence and predictability.

Predictors of difficult airway: preoperative assessment

A prominent acromegalic facial appearance was not present.

McCune Albright syndrome in association with excessive GH secretion: case report

Long-term results of transsphenoidal pituitary microsurgery in 60 acromegalic patients.

Ultrasonographic assessment of soft tissues in patients with acromegaly

Pathologies of the somatotrophic axis must be excluded in a young patient with an acromegalic phenotype, before considering other differential diagnoses, such as pseudoacromegaly associated with severe insulin resistance or pachydermoperiostosis (3).

Pachydermoperiostosis: a rare clinical entity/Pakidermoperiostozis: nadir bir klinik antite

Effects of treatment with somatostatin analogues on QT interval duration in acromegalic patients.