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Related to acromegalic: acromegalic gigantism


A chronic disorder caused by overproduction of human growth hormone usually by the pituitary gland, characterized by enlargement of the bones of the extremities and the skull and often by the development of complications such as diabetes, hypertension, and osteoarthritis.

[French acromégalie : Greek akron, top, extremity (from neuter of akros, extreme; see acro-) + Greek megas, megal-, big; see meg- in Indo-European roots.]

ac′ro·me·gal′ic (-mĭ-găl′ĭk) adj. & n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.acromegalic - marked or affected by enlargement or hypertrophy of the extremities or the face; "a protruding acromegalic jaw"
unshapely - not well-proportioned and pleasing in shape; "a stout unshapely woman"
References in periodicals archive ?
Other complaints were decreased level of consciousness, decreased vision, vomiting, hearing loss, acromegalic features, numbness, proptosis, cerebrospinal fluid (CSF) rhinorrhoea, altered behaviour, ataxia, blindness, dysphagia, oculomotor nerve palsy, diplopia, vertigo, monoplegia, post-auricular discharge and tinnitus.
An SSTR5 mutation in tumor tissue was reported in one acromegalic patient who was resistant to SST analog treatment, which implies a role for SSTR5 in predicting response.
Early postoperative indicators of late outcome in acromegalic patients.
14] showed that significant increase in GH level in acromegalic patients group compared to control group.
Control of tumor size and disease activity during cotreatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient.
The aim of this study was to investigate association between the frequencies of LEP and LEPR gene polymorphisms and subclinical atherosclerosis in acromegalic patients.
Acromegalic patients have a deficient activation of brain areas associated with memory, in this case, the temporal and prefrontal region.
Difficult intubation in acromegalic patients: incidence and predictability.
A prominent acromegalic facial appearance was not present.
Long-term results of transsphenoidal pituitary microsurgery in 60 acromegalic patients.
Pathologies of the somatotrophic axis must be excluded in a young patient with an acromegalic phenotype, before considering other differential diagnoses, such as pseudoacromegaly associated with severe insulin resistance or pachydermoperiostosis (3).
Effects of treatment with somatostatin analogues on QT interval duration in acromegalic patients.