acromegaly


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ac·ro·meg·a·ly

 (ăk′rō-mĕg′ə-lē)
n.
A chronic disorder caused by overproduction of human growth hormone usually by the pituitary gland, characterized by enlargement of the bones of the extremities and the skull and often by the development of complications such as diabetes, hypertension, and osteoarthritis.

[French acromégalie : Greek akron, top, extremity (from neuter of akros, extreme; see acro-) + Greek megas, megal-, big; see meg- in Indo-European roots.]

ac′ro·me·gal′ic (-mĭ-găl′ĭk) adj. & n.

acromegaly

(ˌækrəʊˈmɛɡəlɪ)
n
(Pathology) a chronic disease characterized by enlargement of the bones of the head, hands, and feet, and swelling and enlargement of soft tissue, esp the tongue. It is caused by excessive secretion of growth hormone by the pituitary gland. Compare gigantism
[C19: from French acromégalie, from acro- + Greek megal-, stem of megas big]
acromegalic adj, n

ac•ro•meg•a•ly

(ˌæk rəˈmɛg ə li)

n.
a disorder of the pituitary gland involving excessive production of growth hormone and resulting in enlargement of the head, hands, and feet.
[1885–90; < French < New Latin]
ac•ro•me•gal•ic (ˌæk roʊ məˈgæl ɪk) adj.

acromegaly

Medicine. a disease resulting from abnormal activity of the pituitary gland in which bones of the extremities are enlarged. — acromegalic, adj., n.
See also: Body, Human
Medicine. a disease resulting from abnormal activity of the pituitary gland in which bones of the extremities are enlarged. — acromegalic, adj.
See also: Bones
Medicine. a disease resulting from abnormal activity of the pituitary gland in which bones of the extremities are enlarged. — acromegalic, adj.
See also: Size
a disease resulting from abnormal activity of the pituitary gland, causing bones of the extremities to become enlarged. — acromegalic, adj.
See also: Disease and Illness
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.acromegaly - enlargement of bones of hands and feet and faceacromegaly - enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor)
hyperpituitarism - excessive activity of the pituitary gland (especially overactivity of the anterior lobe which leads to excess secretion of growth hormone)
hypertrophy - abnormal enlargement of a body part or organ
Translations
акромегалия
akromegalie
Akromegalie
akromegalia
acromégalie
אקרומגליה
先端巨大症
acromegalie
akromegali
akromegalia
akromegália
акромегалија
akromegali
akromegali
акромегалія

ac·ro·meg·a·ly

[MIM*102200]
n. acromegalia, enfermedad crónica de la edad madura manifestada por un agrandamiento progresivo de las extremidades óseas y los huesos de la cabeza debido a un malfuncionamiento de la pituitaria.

acromegaly

n acromegalia
References in periodicals archive ?
A possible Association between manganese superoxide dismutase genotypes and antioxidants markers in acromegaly patients.
Background: Acromegaly is associated with increased morbidity and mortality related to cardiovascular diseases.
Cognitive dysfunctions associated with acromegaly may be justified by the fact that changes in structure and function occur in time and they are not fully reversible even if GH and IGF1 values normalize under treatment.
Som is a Swiss/US based biopharmaceutical company focused on developing novel somatostatin analogue peptide medicines for patients with rare neuroendocrine diseases with high unmet need, principally focused on additional orphan drug candidates to address acromegaly and Cushing's disease.
[USPRwire, Mon Feb 01 2016] Global Markets Direct's, 'Acromegaly - Pipeline Review, H2 2015', provides an overview of the Acromegaly's therapeutic pipeline.
The doctor may be found negligent for missing the diagnosis of acromegaly and accompanying sleep apnea, and for failing to treat and warn about driving risks.
Obstructive sleep apnea is a well-recognized complication of acromegaly with its bony and soft-tissue hypertrophy.
Excessive production of growth hormone (GH) and insulin-like growth factor (IGF) results in the development of acromegaly. This multisystem disease usually begins between 25 and 40 years of age and occurs at similar rates among men and women (1-3).
(7) Acromegaly: 50% of patients with growth hormone adenomas were associated with hyperprolactinemia.[sup][1] (c) Drug factors, some drugs increased secretion of prolactin by antagonizing prolactin release inhibitory factor and increasing prolactin-releasing factor leading to reducing the role of dopamine.
Acromegaly is a clinical syndrome resulting from excessive production of growth hormone (GH).
Therefore, the term "excessive GH secretion" is used instead of "acromegaly" (3, 4).
Progressive enlargement of the hands and feet is also observed in acromegaly (1).