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A protein that forms the microfilaments of the eukaryotic cytoskeleton and plays an important role in cell movement, shape, and internal organization. In muscle cells, it functions with myosin to produce contraction.

[Latin āctus, motion; see act + -in.]


(Biochemistry) a protein that participates in many kinds of cell movement, including muscle contraction, during which it interacts with filaments of a second protein, myosin
[C20: from act + -in]


(ˈæk tən)

a protein that functions in muscular contraction by combining with myosin. Compare actomyosin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.actin - one of the proteins into which actomyosin can be split; can exist in either a globular or a fibrous form
actomyosin - a protein complex in muscle fibers; composed of myosin and actin; shortens when stimulated and causes muscle contractions
simple protein - a protein that yields only amino acids when hydrolyzed
References in periodicals archive ?
Achieve a molecular scale understanding of cooperative and competitive relationships between regulators at microtubule ends, and their effect on microtubule dynamics, microtubule behavior at the cell boundary, and interactions with actin filaments.
For example, it controls the building up and breaking down of actin filaments.
2+] ions concentration [8, 9], the content of which determines the depolymerization of actin filaments during the swelling among many cell types [10].
Microtubules (red) and actin filaments (purple) help give the synaptic bouton structure and move cargo around inside the neuron.
He said that they have discovered that Plasmodium actin filaments are very different from other actin filaments and now that they know the structural basis for this, we can look for ways to specifically interfere with the parasite cytoskeleton to the of this protein in the parasite in high detail.
myosin motor proteins which hydrolyze ATP (adenosine triphosphate), and thin actin filaments.
Actin filaments provide a cell with the ability to contract.
Various reported substrates of parkin include CDC-rel-1, O-glycosylated a-synuclein, the parkin-associated endothelin-like receptor, the [alpha]-synuclein--binding protein synphilin-1, actin filaments, the poly(Q)expanded mutant of ataxin-3, Huntington disease polyglutamine proteins, the amyloidogenic Alzheimer disease A[beta] 1-42 peptide (amyloid-[beta] peptide 1-42), and a[beta]-tubulin.
The actin filaments are made of a double helix of actin molecules with troponin molecules localized in certain intervals.
Actin filaments are also required for meiotic spindle rotation in Xenopus and sheep oocytes.
Treatment with actein altered the distribution of actin filaments and induced apoptosis in these cells.
Another mechanism leading to cholestasis is mediated by drugs that bind to actin filaments, resulting in disruption of the actin filaments situated around the bile canaliculi, thus preventing the normal pulsatile contractions that move bile through the canalicular system to the bile ducts (Cullen 2005).