macrophage(redirected from activated macrophage)
Also found in: Thesaurus, Medical, Encyclopedia.
Any of various large, phagocytic white blood cells that develop from monocytes, are found in the spleen, liver, and other tissues, and have a variety of functions in the immune system including engulfing and destroying pathogens and dead cells, presenting antigens to activate lymphocytes, and releasing cytokines that mediate inflammation.
mac′ro·phag′ic (-făj′ĭk) adj.
(Zoology) any large phagocytic cell occurring in the blood, lymph, and connective tissue of vertebrates. See also histiocyte
a large white blood cell, occurring principally in connective tissue and in the bloodstream, that ingests foreign particles and infectious microorganisms by phagocytosis.
[< German Makrophagen (pl.) (Metchnikoff, 1887), with -phagen representing Phagozyten phagocytes; see macro-, -phage]
mac`ro•phag′ic (-ˈfædʒ ɪk) adj.
Any of the large white blood cells in many vertebrates that engulf and break down foreign particles and bacteria in blood or lymph. Macrophages are important in the body's defense against disease and are found mainly in the spleen, lymph nodes, and liver.
n. macrófago, célula mononuclear fagocítica;
___ migration → migración de ___ -s.