active placebo


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Noun1.active placebo - a placebo used in experimental tests of a drug that has noticeable side effectsactive placebo - a placebo used in experimental tests of a drug that has noticeable side effects; "an active placebo mimics the side effects of the experimental drug"
placebo - an innocuous or inert medication; given as a pacifier or to the control group in experiments on the efficacy of a drug
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Nevertheless, the use of an active placebo may have made omega-3 fatty acids appear slightly less effective than they actually were.
Maurizio Fava, M.D., from Massachusetts General Hospital in Boston, and colleagues compared a range of intravenous (IV) ketamine doses to active placebo for the treatment of TRD in 99 adult outpatients (aged 18 to 70 years) for a three-day period following a single infusion over 40 minutes.
The lowest dose served as an "active placebo." Neither the researchers nor the subjects knew who was receiving which amount.
We now know that exposing consumers to these messages turns an innocuous ingredient into an active placebo. Even if these effects are only fantasized, their consequences are nonetheless real.
Each subject will be randomly given either a full dose -- 125 milligrams of MDMA, or an "active placebo" dose of 30 milligrams, Burge said.