active site


Also found in: Thesaurus, Medical, Legal, Financial, Encyclopedia, Wikipedia.

active site

n.
The part of an enzyme at which catalysis of the substrate occurs.

ac·tive site

(ăk′tĭv)
The part of an enzyme where the substance that the enzyme acts upon (called the substrate) is catalyzed. See more at enzyme.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.active site - the part of an enzyme or antibody where the chemical reaction occurs
site, situation - physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides"
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
References in periodicals archive ?
Here, we present a reliable bioinformatics classroom module into an introductory biochemistry course, which identifies two critical aspects of hands-on activity: building phylogeny and 3D structure of the active site of the target enzyme, [alpha]-amylase.
Argonne's Porous Nano-Network Catalyst revolutionizes the nonprecious metal catalyst design and synthesis simultaneously at the active site and electrode architecture levels.
Applications are open to athletes, who live in a district or borough with an Everyone Active centre or who are already a member of an Everyone Active site.
Three dimensional structures of lipases have demonstrated the presence of various conserved domains including active site motif, metal binding pocket, a/AY hydrolase fold and regulatory elements binding domains [4, 5].
Contract notice: Annual road management for the active site residenzstraE-e.
For example, a drug that binds into the active site of an enzyme can inhibit its important biological function and stop the enzyme from working.
Mr Curtain said: "Visits like these also give us an opportunity to talk to local youngsters about health and safety and the importance of taking care around an active site.
The peculiar feature of lipases is the presence of a/AY hydrolase fold in the N-terminal domain which contains a buried active site in the form of a catalytic triad which is similar to the catalytic site of chemotrypsin, trypsin, serine proteases and other esterases (Brzozowski et al.
For the first time, Pierce's team found that mutations outside the CDO active site environment or "outer coordination sphere" have a profound influence on the release of ROS.
The fixation of the particulate photocatalyst on a large inert substrate reduces the surface of the photocatalytic active site and also enlarges the mass transfer limitation of pollutants to the photocatalytic active site since binder chemicals used for the fixation of particulate photocatalysts are often deposited on the surface of photocatalysts, resulting in the decrease of the surface active site.
Aa], the active site of DAT is predicted to be comprised of residues from TMs 1, 3, 6, and 8 (2).
MECHANISM OF ACTION OF NEWER ANTICOAGULANTS: Thrombin-inhibiting drugs can block the action of thrombin by binding to three domains: the active site or catalytic site and two exosites.

Full browser ?