leukemia

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leu·ke·mi·a

 (lo͞o-kē′mē-ə)
n.
Any of various acute or chronic neoplastic diseases of the bone marrow in which unrestrained proliferation of white blood cells occurs, usually accompanied by anemia, impaired blood clotting, and enlargement of the lymph nodes, liver, and spleen.

leu·ke′mic adj. & n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

leu•ke•mi•a

(luˈki mi ə)

n.
any of several cancers of the bone marrow characterized by an abnormal increase of white blood cells in the tissues.
[earlier leuchaemia < German Leukämie (1848). See leuko-, -emia]
leu•ke′mic, adj., n.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

leu·ke·mi·a

(lo͞o-kē′mē-ə)
Any of several cancers of the blood in which abnormal white blood cells multiply uncontrollably, eventually crowding out normal cells in the bone marrow.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

leukemia

a malignancy of blood-producing tissues, characterized by proliferating immature white blood cells and infiltration of the spleen, liver, and other organs. Also leukocythemia.leukemie, leukemoid, adj.
See also: Cancer
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.

leukemia

Cancer of the white blood cells. It affects the tissues involved in the production of blood, such as the bone marrow and lymph nodes.
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.leukemia - malignant neoplasm of blood-forming tissuesleukemia - malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer
cancer, malignant neoplastic disease - any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream
acute leukemia - rapidly progressing leukemia
chronic leukemia - slowly progressing leukemia
lymphocytic leukemia - leukemia characterized by enlargement of lymphoid tissues and lymphocytic cells in the circulating blood
histiocytic leukaemia, histiocytic leukemia, monoblastic leukaemia, monoblastic leukemia, monocytic leukaemia, monocytic leukemia - leukemia characterized by the proliferation of monocytes and monoblasts in the blood
myeloblastic leukemia - a malignant neoplasm of blood-forming tissues; characterized by numerous myeloblasts in the blood stream
granulocytic leukemia, myelocytic leukemia - a malignant neoplasm of blood-forming tissues; marked by proliferation of myelocytes and their presence in the blood
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
الّلُوكِيمْيَاسرطان الدم
leukémieleukemie
leukæmi
leukemia
סרטן הדם
leukemijabjelokrvnost
fehérvérűségleukémia
kanker darahleukemia
blóðlýsahvítblæði
白血病
백혈병
leucemie
leukemi
โรคที่มีเม็ดโลหิตขาวมากเกินไป
bệnh bạch cầu

leukaemia

(American) leukemia (luːˈkiːmiə) noun
a disease that causes white blood cells to multiply abnormally in the body.
Kernerman English Multilingual Dictionary © 2006-2013 K Dictionaries Ltd.

leukemia

الّلُوكِيمْيَا leukémie leukæmi Leukämie λευχαιμία leucemia leukemia leucémie leukemija leucemia 白血病 백혈병 leukemie leukemi białaczka leucemia лейкемия leukemi โรคที่มีเม็ดโลหิตขาวมากเกินไป lösemi bệnh bạch cầu 白血病
Multilingual Translator © HarperCollins Publishers 2009

leu·ke·mi·a

n. leucemia, cáncer de la sangre;
acute lymphocytic ______ linfoncítica aguda;
aleukemic ______ aleucémica;
chronic granulocytic ______ granulocítica crónica;
chronic ______ crónica;
chronic myeloid ______ mieloide crónica;
eosinophilic ______ eosinofílica;
lymphocytic ______ linfocítica;
monocytic ______ monocítica.
English-Spanish Medical Dictionary © Farlex 2012

leukemia

n leucemia; acute lympho-blastic o lymphocytic — leucemia linfoblástica or linfocítica aguda; acute myeloid — leucemia mieloide aguda; chronic lymphocytic — leucemia linfocítica crónica; chronic myeloid — leucemia mieloide crónica
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Acute Promyelocytic Leukemia (APL) classified as AML M3 according to French-American-British (FAB) classification system and APL with t(15;17) and PML RAR[alpha] by WHO is a distinct subtype of Acute Myeloid Leukemia (AML)1.
Diffuse alveolar hemorrhage in acute promyelocytic leukemia patients treated with ATRA - A manifestation of the basic disease or the treatment.
* Arsenic trioxide is a promising drug used for the treatment of acute promyelocytic leukemia (APL).
In our study, we have reported two patients of acute promyelocytic leukemia having complex karyotype with translocation (15;17).
Upon completion of the first 28 days of induction therapy, repeat lumbar puncture and bone marrow studies demonstrated no morphologic evidence of acute promyelocytic leukemia, consistent with remission.
KEY WORDS: Acute Promyelocytic Leukemia; Promyelocytes; QT Prolongation; Torsades De Pointes; Arsenic Trioxide
PML-RARA testing was reportedly performed 97.7% (213 of 218) of the time for all or selected patients suspected of having acute promyelocytic leukemia. Testing for mutations in FLT3 and NPM1 was performed for all patients by 51.4% (109 of 212) and 46.9% (98 of 209) of respondents, respectively, and for selected cases by 45.8% (97 of 212) and 47.8% (100 of 209), respectively, of respondents.
Although acute promyelocytic leukemia (APL) accounts for 12-15% of therapy-related AML (t-AML), these cases typically occur following chemotherapy with topoisomerase II inhibitor and only occasionally following radiation therapy.
Acute promyelocytic leukemia (APL) is a distinct form of acute myeloid leukemia (AML) characterized by the balanced translocation t(15;17)(q24;q21) that results in production of the PML-RARA oncogene.
The notable exception being acute promyelocytic leukemia (APL) with the development of alltrans retinoic acid (ATRA) and arsenic trioxide (ATO) to overcome the block in myeloid differentiation due to the PML-RARa fusion protein created by the translocation 15;17.
The successful example of the acute promyelocytic leukemia, nowadays treated in the majority of the cases without chemotherapy by regimen based on the combined use of retinoic acid and arsenic trioxide [2], is worth mentioning.
Aside from those patients with chronic myeloid leukemia (CML) induced by wild-type BCR-ABL fusion protein or those with acute promyelocytic leukemia (APL) caused by reciprocal chromosomal translocation of the retinoic acid receptor a (RARa) gene, most patients have a poor prognosis [2, 3].

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