adalimumab


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ad·a·lim·u·mab

 (ăd′ə-lĭm′o͞o-măb′)
n.
A human monoclonal antibody that blocks the action of tumor necrosis factor and is used to treat certain autoimmune disorders, especially rheumatoid arthritis, Crohn's disease, and psoriasis.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations

adalimumab

n adalimumab m
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Safety of Adalimumab Treatment in Crohn's Disease with Fistula.
Adalimumab, unlike traditional disease modifying antirheumatic drugs (DMARDs), has a significant effect on patient disease after one week of treatment.
Merck KGaA, Darmstadt, Germany, has initiated a global Phase III study of MSB11022, a proposed biosimilar of adalimumab, in chronic plaque psoriasis.
Herein, we present a case of Chinese man with a 10-year history of RA developing crescentic immunoglobulin A (IgA) nephritis and multiple autoantibodies during adalimumab treatment.
We report a case of severe recalcitrant DCS successfully treated with adalimumab. [P R Health Sci J 2015;34:102-104]
Humira (adalimumab) is a recombinant, fully-human, IgG1 mAb that binds to TNFa and blocks its interaction with the p55 and p75 cell-surface receptors, which reduces inflammation and prevents tissue destruction.
Tocilizumab used with methotrexate was superior to adalimumab used with methotrexate
BALTIMORE--Exposure to adalimumab was not associated with any specific pattern of minor or major birth defects in women with rheumatoid arthritis taking the biologic drug during pregnancy, according to preliminary data from an ongoing prospective cohort study.
The trial will test how effective the drug adalimumab is for youngsters with a strain of the disease called juvenile idiopathic arthritis (JIA).
TNF blocker drugs, such as adalimumab (Humira), etanercept (Enbrel) and infliximab (Remicade), bind to tumor necrosis factor-alpha, rendering it inactive and interfering with inflammatory activity.