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New England Consulting Group Analysis Ditterin Adapalene (Brand RX) '12 $311.72 Adapalene Gel (Generic RX)'12 $156.58 Ditterin Adapalem Gel (Brand OTC) '19 $29.99 Adapalene Gel (Generic OTC)'19 Not Applicable Differing Adapalene Gel (0.1%, 45 grams) Nexium Esomeprazole (Brand Rx) * '13 $297.53 Esomeprazole (Generic Rx '19) $238.02 Nexium Esomeprazole 24 HR (Brand OTC)* '19 $23.00 Walgreens Esomeprazole Magnesium (Brand OTC)* '19 $21.30 Nexium Esomperazole (30 ct, 20 mg) Xyzal Levocetirizine (Brand Rx)* '15 $101.55 Levocetirizine (Generic Rx)'15 $82.97 Xyzal Levocetirizine Allergy 24 HR (Brand OTC)* '19 $19.71 Walgreens Levocetirizine (Brand OTC)* '19 $13.80 Xyzal Levocetirizine (30 ct, 5 mg) Sources:,,
The topical retinoid adapalene 0.3% gel alleviated scarring in patients with moderate or severe atrophic acne scars but no active disease.
"I suggest Differin, which is available OTC and uses adapalene, an active retinoid, to balance skin cell production and reduce inflammation."
PARIS -- Treatment with the fixed combination adapalene 0.3%/benzoyl peroxide 2.5% gel not only reduced facial acne lesions, it also decreased the atrophic acne scar count in a multicenter, randomized trial, Brigitte Dreno, MD, reported at the annual congress of the European Academy of Dermatology and Venereology.
Topical agents for treatment include eclotrimazole, selenium sulfide (2.5% to 5%) shampoo, ketoconazole shampoo, zinc pyrithione, nystatin, 3% salicylic acid, topical terbinafine, tretinoin, 1% diclofenac gel and adapalene gel.
This treatment combines benzoyl peroxide and adapalene. Epiduo helps tone down inflammation so it works for red and inflamed pimples.
And it now has competitors: Tazarotene also requires a prescription, but adapalene (which the FDA has approved only for treating acne) is sold over the counter as Differin.
The Food and Drug Administration's approval of adapalene gel 0.1 percent as an over-the-counter treatment for acne is a potential game changer that could lead to revision of guideline-recommended treatment algorithms.
A similar study was conducted in which mild to moderate acne was improved in 8 weeks.14 Babaeinejad and Fouladi15 (2013) found that benzoyl peroxide 2.5% gel is less effective than topical adapalene 0.1% gel.
Healthcare company Perrigo Company plc (NYSE:PRGO) (TASE:PRGO) revealed on Wednesday the availability of an AB rated generic version of Epiduo (adapalene and benzoyl peroxide) Gel, 0.1%/2.5% for acne vulgaris.
A representative retinoid agent, adapalene, is used as a key drug during all stages of acne vulgaris.