Classification of gastric polyps (The British Society of Gast-roenterology, 2009) Non-mucosal Intramural Epithelial Polyps Polyps Fundic gland polyp Gastrointestinal stromal tumor Hyperplastic polyp Leiomyoma
Adenomatous polyp Inflamatoryfibroid polyp Hamartomatous polyp Fibromaand fibromyoma * Juvenile polyp Lipoma * Peutz-Jeghers' syndrome Ectopic pancreas * Cowden's syndrome Neurogenic and vascular Polyposis syndromes tumours (non-hamartomatous) Neuroendocrine tumours * Juvenile polyposis (carcinoids) * Familial adenomatous polyposis Table 2.
But if you have a first degree relative with either colon cancer or an
adenomatous polyp, don't wait until you're 50 and start your regular screening by the age of 40, or at least 10 years younger than the affected relative.
Among the 65 colorectal polyps, 50 cases were
adenomatous polyps and tubular adenomas constitute the predominant type of
adenomatous polyp.
The most common type was the
adenomatous polyp in 88(55.0%) cases followed by hyperplastic polyps 51(31.9%) and inflammatory polyps 21(13.1%).
Comparison of the metabolic profiles of human
adenomatous polyp (N = 61) and colorectal cancer (CRC) (N = 57) tissue found statistically significant differences (p < 0.05) in their composition of adenosine monophosphate (AMP), adenine, 5'-methythioadenosine, 3-hydroxybutyric acid, prostaglandin E2, threonine, and glutamine.
* average risk of developing colorectal cancer (no personal history of
adenomatous polyps, of colorectal cancer, or inflammatory bowel disease, including Crohn's Disease and ulcerative colitis; no family history of colorectal cancers or an
adenomatous polyp, familial adenomatous polyposis, or hereditary nonpolyposis colorectal cancer).
A) 672 adults from the Nurses' Health Study and the Health Professionals Follow-up Study with a history of
adenomatous polyp formation
Given that most sporadic CRCs develop from
adenomatous polyps, it has been shown that CRC risk can be reduced by removal of the precursor lesion, the
adenomatous polyp.
The important fact is that colon cancers develop from
adenomatous polyps by growing larger and eventually transforming into cancer; it is believed to take about 5 to 10 years for an
adenomatous polyp to grow into cancer.
A PREVIOUS POLYP OR COLORECTAL CANCER: Not all types of polyps increase the risk of bowel cancer, but a type called
adenomatous polyp does.
Results: The risk of
adenomatous polyp recurrence was inversely related to alpha-carotene concentrations and right-sided polyps; alpha-carotene intake and recurrence of any, multiple and right-sided polyps; beta-carotene intake and multiple adenoma recurrence; and vitamin A from food and dietary supplements and each adverse endpoint.
For example, it takes an average of 15 to 20 years for a small
adenomatous polyp to become malignant.
