Rigid cyst formation is an architectural pattern also frequently seen in adenosarcoma
. Large cystic spaces lined by benign epithelium are surrounded by low-grade malignant stroma (hematoxylin-eosin; original magnification X200).
In differential diagnosis, mullerian adenosarcoma
should be considered.
A graver potential pitfall in the differential diagnosis is an extension of a Mullerian adenosarcoma
of the cervix into the vulva.
These include Adenomyoma, Embryonal rhabdomyosarcoma, Leiomyoma, and even lesions like Schwannoma, Nabothian cyst, Decidualized stroma, Plasmacytoma, Villoglandular papillary adenocarcinoma, Adenosarcoma
, Non-hodgkin's lymphoma, Aggressive angiomyxoma, Gliosis of cervix etc.
(11,20-25) Other conditions that may enter into the differential diagnostic consideration less frequently are adenosarcoma
, carcinosarcoma, perivascular epithelioid cell tumor, and adenomatoid tumor.
Clement, MD, he described the uterine Mullerian adenosarcoma
and later published the largest study of the subject.
(46,47) The main differential diagnosis is mullerian adenosarcoma
, which characteristically shows leaflike glandular architecture, periglandular stromal hypercellularity, and atypical stromal cells, features absent in polypoid endometriosis.
They include adenosarcoma
, carcinosarcoma, malignant mixed mullerian tumor, pulmonary blastomas, and biphasic mesotheliomas.
in a young adult: morphologic, immunophenotypic, ultrastructural, and fluorescence in situ hybridization analyses: a case report and review of the literature.
of the cervix that secondarily involves the vulva may imitate a PT due to the formation of polypoid mass, a similar leaf-like architecture, and biphasic pattern.
Laparoscopic management of 15 patients with infiltrating endometriosis of the bladder and a case of primary intravesical endometrioid adenosarcoma
. Fertil Steril.
(MA) of ovary with sarcomatous (rhabdomyoblastic) overgrowth is an extremely rare malignant type of female genital tract neoplasm.