Inhibitory and stimulatory G proteins of adenylate cyclase
In order to investigate the role of cyclic GMP and the cyclic AMP relaxing pathways in the MeOH-Sc effects, assays were performed in the presence of inhibitors of adenylate cyclase
(SQ 22536) and soluble guanylate cyclase (ODQ).
125]I]IHYP (iodohydroxybenzylindolol), and the component with GppNHp-activated adenylate cyclase
activity could be physically separated as distinct entities.
Shedding of membarane bounf CD 14 from lipopolysacharide and pituitary adenylate cyclase
After internalization, S1 transfers the ADP-ribose moiety of NAD to the Gi regulatory component of the adenylate cyclase
The W07-toxin could also cause elevation in the adenylate cyclase
dependent-cAMP levels in mice enterocytes.
This pathway is composed of Ras proteins (encoded by RAS1 and RAS2 GTPases) that consecutively activate adenylate cyclase
(encoded by CDC35 in C.
Rapid antidepressant response to alprazolam in depressed patients with high catecholamine output arid heterologous desensitization of platelet adenylate cyclase
Cannabinomimetic behavioral effects of and adenylate cyclase
inhibition by two new endogenous anandamides.
Although both FSH and LH act through stimulatory G protein-coupled receptors (GCPRs), activation of adenylate cyclase
and production of the second-messenger cyclic adenosine monophosphate (cAMP, Jonassen et al.
Topics include specialization in Bordetella as deduced from comparative genome analysis; the phylogeny, evolution and epidemiology of Bordetellae; the bvg regulon; Bordetella adhesins and toxins; Ptl Type III secretions in Bordetella subspecies; Ptl Type IV secretion systems; primary metabolism of physiology; bacteriophage and diversity-generating retroelements; biotechnological applications of the Bordetella pertussis adenylate cyclase
toxin; and pertussis vaccines.
In the mouse sperm, adenylate cyclase
activity (which is involved in the production of cyclic adenosine monophosphate, cAMP) increased in a timedependent manner simultaneously with a decrease in phosphodiesterase activity [5,28,34].