adenylate cyclase

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Related to adenylate cyclase: cyclic AMP, Phospholipase C, Protein kinase A

a·den·yl·ate cyclase

(ə-dĕn′əl-ĭt, ăd′n-ĭl′ĭt) also a·den·yl cyclase (ə-dĕn′əl, ăd′n-ĭl)
An enzyme that catalyzes the formation of cyclic AMP from ATP and plays a key role in signal transduction.

References in periodicals archive ?
In order to investigate the role of cyclic GMP and the cyclic AMP relaxing pathways in the MeOH-Sc effects, assays were performed in the presence of inhibitors of adenylate cyclase (SQ 22536) and soluble guanylate cyclase (ODQ).
125]I]IHYP (iodohydroxybenzylindolol), and the component with GppNHp-activated adenylate cyclase activity could be physically separated as distinct entities.
Shedding of membarane bounf CD 14 from lipopolysacharide and pituitary adenylate cyclase activating.
After internalization, S1 transfers the ADP-ribose moiety of NAD to the Gi regulatory component of the adenylate cyclase complex.
The W07-toxin could also cause elevation in the adenylate cyclase dependent-cAMP levels in mice enterocytes.
This pathway is composed of Ras proteins (encoded by RAS1 and RAS2 GTPases) that consecutively activate adenylate cyclase (encoded by CDC35 in C.
Rapid antidepressant response to alprazolam in depressed patients with high catecholamine output arid heterologous desensitization of platelet adenylate cyclase.
Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides.
Although both FSH and LH act through stimulatory G protein-coupled receptors (GCPRs), activation of adenylate cyclase and production of the second-messenger cyclic adenosine monophosphate (cAMP, Jonassen et al.
Topics include specialization in Bordetella as deduced from comparative genome analysis; the phylogeny, evolution and epidemiology of Bordetellae; the bvg regulon; Bordetella adhesins and toxins; Ptl Type III secretions in Bordetella subspecies; Ptl Type IV secretion systems; primary metabolism of physiology; bacteriophage and diversity-generating retroelements; biotechnological applications of the Bordetella pertussis adenylate cyclase toxin; and pertussis vaccines.
In the mouse sperm, adenylate cyclase activity (which is involved in the production of cyclic adenosine monophosphate, cAMP) increased in a timedependent manner simultaneously with a decrease in phosphodiesterase activity [5,28,34].