In the postdoctoral category, first was Vimal Ramachandran with the poster A microRNA-based strategy to combat hypercholesterolemia; and joint second were Murugan Subramanian with A microRNA-dependent pathway regulating ER stress-induced lipogenesis via mTOR in liver; and Yasser Majeed with Functional interaction between Sirt1 deacetylase and Myc oncogene regulates adipogenesis
When VD supplies are low (intake of diet deficient in VD), the enzymatic capacity of non-renal tissues (adipose tissue) to produce 1,25 (OH)2D is diminished, stimulating adipogenesis
, which is accordingly with our findings.
The inhibition of adipogenesis
results in adipose tissue fibrosis, which leads to ectopic adiposity and acts as a causative factor for the development of insulin resistance in the various target organs.
In addition, the researchers showed that Cbf-beta maintains the osteoblast lineage commitment in two ways: through the Wnt paracrine pathway to affect nearby cells and through endogenous signaling within the cell to suppress adipogenesis
In addition, a study in murine stem cells showed that the FM550 components TPP and IPTP divert osteogenesis to the adipogenesis
pathway through activation of peroxisome proliferatoractivated receptor [gamma] (PPAR[gamma]) (Pillai et al.
Degenerative muscle fiber accelerates adipogenesis
of intramuscular cells via rhoa signaling pathway.
Many previous studies have discovered that retinoic acid has an inhibitory effect on adipogenesis
in 3T3-L1 cell [15-17].
sup],, Furthermore, both in vivo and in vitro studies have indicated that the MRF2/ARID5B gene may affect adipogenesis
Experimental studies have shown that BPA is a selective modulator of estrogen receptors and that it accelerates adipogenesis
and body growth.
Purpose: Here we report the effects of MA on the adipogenesis
process in 3T3-L1 cells.
Adiponectin an adipose tissue-specific protein is normally under transcriptional control of adipogenesis
regulators comprising; PPAR-[gamma] (peroxisome-proliferator activated receptor gamma), SREBP-lc (sterol regulatory element binding protein-lc), C/EBP-[alpha], (CCAAT enhancer binding protein alpha) and ID-3 protein [25-28].
Posible rol activo de micronutrientes en la regulacion de genes relacionados con la adipogenesis
, inflamacion y el metabolismo energetico (6).