The largest study on serum adiponectin
levels in breast cancer patients is reported from South Korea.
The authors also noted an increase in the values of anti-inflammatory adiponectin
, an adipokine again connected with glucose maintenance and insulin sensitivity.
showed that BMI was significantly higher and the serum adiponectin
level was significantly lower in gastritis-positive patients than in gastritis-negative patients (7).
, an adipokine belonging to the complement factor C1Q protein family , is expressed in liver sinusoid endothelial cells, skeletal muscle and bone-forming cells as well as in adipocytes [2-4].
is a protein hormone with anti-inflammatory and insulin-sensitizing properties that plays an important role in a number of metabolic processes such as glucose regulation and fatty acid oxidation.
Each of seven mice per group was selected using blood glucose levels and body weight, and the changes in the body weight, epididymal fat weights, serum adiponectin
and leptin levels, adipose adiponectin
contents and liver triglyceride contents were monitored.
According to an Endocrine Society-led study, race and pre-pregnancy body mass index (BMI) both affect leptin and adiponectin
is mostly produced in adipose tissue .
, a bioactive adipocytokine exclusively secreted by mature adipocytes in adipose tissue possesses anti-inflammatory, antiatherogenic, and insulin-sensitizing properties.
, an adipocyte-specific cytokine, exhibits anti-inflammatory property and protective effects against obesity-related diseases (6).
The second mechanism is that obesity alters levels of adipokines secreted from adipose tissue (resistin, leptin, adiponectin
, and proinflammatory cytokines such as interleukin-6 and tumor necrosis factor-[alpha]).