In particular, the adipose microtissues can be used to assess human adipogenesis/preadipocyte differentiation, human adipocyte lipolysis, metabolism and the modulation effects on
adipose cell functions derived from treatment with active ingredients, such as food components and additives.
Previous experiments have enabled them to decode a signaling pathway involved in
adipose cell maturation and to show that calories in the nutrient medium influence this process.
Going forward, we want to investigate the environmental factors--particularly the nutrient conditions--that cause different
adipose cell types to grow," said biophysicist Matthias Meier.
Therefore, the practical goals of treatment are to produce good-quality bone (osteogenesis) and to inhibit production of the abnormal
adipose cell intruders (adipogenesis).
The beige adipocyte is a type of
adipose cell described by the ability to induce these cells to produce heat and increase energy expenditure.
Over a number of years they have been observing clients show a more youthful appearance as one of the after effects of
Adipose cell therapy.
Under the deal, both firms will jointly conduct a study titled 'Development and Validation of a Human Brown
Adipose Cell Model', which will seek to further characterise the identity and metabolic function of these cell lines.
In animal models of obesity, a relationship was shown between
adipose cell size and the concentration of macrophages in the stroma vascular fraction of AT (Weisberg et al.
METHODS: Using murine 3T3-L1 adipocytes as a model for
adipose cell biology research, the effects of IGOB131 were investigated on PPAR gamma, adiponectin, and leptin.
The mRNAs for PPAR-[gamma], a central regulator of
adipose cell differentiation, and AdipoR2 were expressed at low levels during the first 3 days but increased markedly after 6 days (Figure 2).
The company is advancing the development of its brown
adipose cell therapy program by evaluating certain cell delivery encapsulation technology that would enable transplanted brown
adipose cells to effectively maintain or regulate normal metabolism in humans.
Retinoids are positive effectors of
adipose cell differentiation.
adipose cell - cells composed of fat