adoptive immunotherapy

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Related to adoptive transfer: Flow cytometry, transgenic

adoptive immunotherapy

n.
A form of immunotherapy used in the treatment of cancer and certain viral infections in which lymphocytes taken from a patient are stimulated, activated, and infused back into the patient.
References in periodicals archive ?
5) promptly inform the Employer of the transfer of the animal up for adoption and adoptive transfer a copy of the contract if the party is a resident of the municipality Graces;
We used data from individual animals in all experiments; however, for adoptive transfer experiments, data were concatenated due to the low number of gated events for T-cell subsets.
He pointed out that different specific-immunotherapeutic modalities, including cancer vaccines and adoptive transfer had been developed and examined in different phases of clinical trials.
Recent preclinical and clinical studies provide evidence that adoptive transfer of in vitro activated T cells can results in significant antitumour responses in vivo upon acquisition of certain survival and homing properties during in vitro activation.
host (GvH) disease and graft rejection; cell therapy to prevent leukemia relapse; modalities to improve immune reconstitution after transplantation; clinical studies on boosting thymus output or using adoptive transfer of immunity against infectious agents or malignant cells; and new approaches to induce immune tolerance towards organ transplantation by hematopoietic stem cell transplantation.
Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma.
In vitro studies and in vivo adoptive transfer experiments revealed that CD4+CD25+ T cells from GM-CSFtreated mice could suppress effector T cell response and T1D.
Consequently, it has become possible to create immune recognition of cancer antigens through immunization and through adoptive transfer of antitumor lymphocytes into a lymphodepleted host.
A novel two-step process called adoptive transfer resulted in more than 50% tumor shrinkage in 6 of 13 patients with malignant melanoma, said Dr.
Adoptive transfer of splenic lymphocytes from immunized animals protected suckling mice against murine rotavirus-induced gastroenteritis in the absence of rotavirus-specific neutralizing antibodies, indicating that antigen-specific CTLs protect against mucosal pathogens in the intestinal tract (32).
Adoptive transfer of immune T cells also conferred protection in the challenge model whereas passive transfer of immune serum did not, indicating the critical role for T cell responses in control of this infection.