adrenarche


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Noun1.adrenarche - the increase in activity of the adrenal glands just before pubertyadrenarche - the increase in activity of the adrenal glands just before puberty
start - the beginning of anything; "it was off to a good start"
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In fact, HS in children may be a marker of precocious puberty, as noted in those presenting with adrenal hyperplasia and premature adrenarche.
Persistence of delayed adrenarche in boys with thalassaemia.
The Pit-1 gene is also responsible for the development of the anterior pituitary [4], inducing the differentiation of hepatic progenitor cells into PRL-producing ones [5] and delaying adrenarche in humans [6].
The absence of 17,20 lyase activity in the adrenal gland also results in deficiency of DHEA sulfate (DHEA-S), causing failure of adrenarche and pubic and axillary hair development (5,6).
Circulating plasma leptin and IGF-1 levels in girls with premature adrenarche: Potential implications of a preliminary study.
The levels of 17a-hydroxyprogesterone and pregnenolone in the healthy boys did not vary significantly among the different adrenarche ages, from approximately 6-8 years old (before puberty initiation) to 9 years old.
(2) Women are at especially high risk if they have a history of oligoovulatory infertility; obesity and/or insulin resistance; diabetes type 1, 2, or gestational; premature adrenarche (stage of puberty when the adrenal cortex begins to secrete androgens, typically signified by pubic and axillary hair growth); any first-degree relatives with PCOS; or use of antiepileptic drugs.
Miller, "Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome," Proceedings of the National Academy of Sciences of the United States of America, vol.
2014), but was inversely associated with odds of having reached adrenarche or pubarche in boys (n =107) (Ferguson et al.
This increment could be explained by the adrenarche, biochemical event with the characteristic increase of SDHEA (exclusive of adrenal synthesis) in which the inner layer of the cortex of the adrenal gland (zona reticularis) is fully developed and secrets androgen of adrenal origin [10].
A diagnosis not to be missed: Non-classic steroid 11E-hydroxylase deficiency presenting with premature adrenarche and hirsutism.