A nerve impulse is a wave of electrical task that passes from one end of afferent neuron
to an additional.
The lack of neurochemical consider the afferent neuron
is also one of the possible causes of this disease.
Increased NGF has been demonstrated in the bladder, dorsal root ganglia, and spinal cord following SCI, and administration of exogenous NGF to the bladder or spinal cord can in animals induce detrusor overactivity and increase bladder afferent neuron
excitability [4, 13].
In addition, the increase in intracolonic pressure also stimulates the serotonin release and activates the 5-HT3 receptors on the terminal of afferent neuron
, inducing intestinal nociceptive transmission to the central nervous system.
The results reveal that the gastroprotection by QCT against ethanol-induced mucosal injury is resistant to capsazepene but is vulnerable to indomethacin, suggesting a role for endogenous prostaglandins and not the capsaicin-sensitive afferent neuron
A nerve impulse is a wave of electrical job that passes from one end of afferent neuron
The increase in intracolonic pressure also induces serotonin release, and it will bind to 5-HT3 receptor at the terminal of afferent neuron
, causing intestinal nociceptive transmission to central nervous system.
Various molecules have been identified as afferent neuron
transmitters in vertebrates and invertebrates.
Sadly, the condition usually go undetected as a lot of client will not really feel any kind of pain because of lack of afferent neuron
in the large intestine.
In neurogenic inflammation, local afferent neurons
secrete inflammatory mediators such as neurokinin A, substance P (SP), and calcitonin gene-related peptide which perpetuate inflammation.
During the storage phase, these afferent neurons
fire at low frequencies because the bladder wall is insufficiently stretched.
Regardless of the mechanism, damaged primary afferent neurons
undergo similar changes.