Laboratory work-up showed a normal complete blood count, a negative antinuclear antibodies (ANA) titer, a negative double-stranded DNA, normal levels of inflammatory markers, and negative cryoglobulins and cold agglutinins
. The patient was diagnosed with pernio.
The surface of the red cell membrane contains genetically determined antigens, called agglutinogens, while plasma contains antibodies called agglutinins
. To determine the blood group of a person, his/her red cells are made to react with sera containing agglutinins
Fulminant autoimmune cold-type hemolysis with marked elevation of monothermic cold agglutinins
. Successful therapy with membrane plasmapheresis.
Then there are those tests that actually benefit from a clotting time spent in an incubator, such as cold agglutinins
, and, in fact, some patient tubes for hematology performing CBCs must be warmed before testing, again, due to cold agglutinins
A new test for the detection of weak and 'incomplete' Rh agglutinins
. British J Exp Pathol.
Finally, although it is possible that monoclonal IgM was undetectable in the serum due to the presence of cold agglutinins
or cryoglobulins, however hemolytic anemia was absent and cold agglutinins
Lectin and agglutinins
were purchased from Sigma Aldrich (St.
Venkatesh, "Identity of the immunomodulatory proteins from garlic (Allium sativum) with the major garlic lectins or agglutinins
," International Immunopharmacology, vol.
react with human red cells but they differ in the strength of the reaction with different cells.
(18.) Sofian, M., Sheikholeslami, M., Mahdaviani, F.A., Aghakhani, A., Banifazl, M., Eslamifar, A., Sarmadian, H., Deiri, G., Ramezani, A., Low prevalence of brucella agglutinins
in blood donors in central province of Iran.
Previous studies have confirmed the presence of lysozyme- (McDade & Tripp, 1967a) and mucus-derived agglutinins
(Fisher 1992) in oyster pallial fluid, suggesting an important role for this fluid in the overall microbial defense system.