agonist


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to agonist: Agonist muscle, Dopamine agonist

ag·o·nist

 (ăg′ə-nĭst)
n.
1. Physiology A contracting muscle that is resisted or counteracted by another muscle, the antagonist.
2. A substance that can combine with a receptor on a cell to initiate signal transduction.
3. One involved in a struggle or competition.

[Late Latin agōnista, contender, from Greek agōnistēs, from agōn, contest; see agony.]

agonist

(ˈæɡənɪst)
n
1. (Physiology) any muscle that is opposed in action by another muscle. Compare antagonist2
2. a competitor, as in an agon
[C17: from Greek agōn agon]

ag•o•nist

(ˈæg ə nɪst)

n.
1. a person engaged in a contest, conflict, struggle, etc., esp. the protagonist in a literary work.
2. a person who is torn by inner conflict.
3. a contracting muscle whose action is opposed by another muscle. Compare antagonist (def. 3).
4. a chemical substance capable of activating a receptor to induce a full or partial pharmacological response. Compare antagonist (def. 5).
[1620–30; < Late Latin agōnista < Greek agōnistḗs contestant =agṓn agon + -istēs -ist]

ag·o·nist

(ăg′ə-nĭst)
A muscle that actively contracts to produce a desired movement. Compare antagonist.

agonist

one who contends for a prize in public games. — agonistic, agonistical, adj.
See also: Athletics
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.agonist - the principal character in a work of fictionagonist - the principal character in a work of fiction
antihero - a protagonist who lacks the characteristics that would make him a hero (or her a heroine)
2.agonist - someone involved in a contest or battle (as in an agon)agonist - someone involved in a contest or battle (as in an agon)
contestant - a person who participates in competitions
adversary, antagonist, opposer, resister, opponent - someone who offers opposition
3.agonist - a muscle that contracts while another relaxesagonist - a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"
antagonistic muscle - (physiology) a muscle that opposes the action of another; "the biceps and triceps are antagonistic muscles"
4.agonist - (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
drug - a substance that is used as a medicine or narcotic
biochemistry - the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry
Translations
agonista
agonista
References in periodicals archive ?
M2 PHARMA-March 15, 2018-LIDDS focuses on NanoZolid with cutting edge STING agonist
M2 EQUITYBITES-March 15, 2018-LIDDS focuses on NanoZolid with cutting edge STING agonist
Although GnRH trigger is currently regarded as the best tool for OHSS prevention, intensive luteal support with exogenous administration of estradiol and progesterone or low-dose hCG on the day of oocyte retrieval or on the day of GnRH agonist trigger are required to achieve optimal conception rates due to early luteolysis.
MedImmune has in-licensed 3M's MEDI9197, a novel TLR 7/8 dual agonist entering Phase I development to explore the safety and tolerability of MEDI9197 as a potential treatment for patients with solid tumors.
Besides, the Nurr1 expression in cultured PBMC was measured to determine whether DA agonist pramipexole affects its mRNA level.
The study among 552 young-adult injecting-drug users, who were followed for 680 person-years, documented 171 cases of HCV infection, but found the rate of infection was significantly lower among those on opioid agonist maintenance therapy, compared with those on non-opioid agonist treatment or opioid agonist detoxification therapy.
The study among 552 young-adult injecting drug users, who were followed for 680 person-years, documented 171 cases of HCV infection, but found the rate of infection was significantly lower among those on opioid agonist maintenance therapy, compared with those on non--opioid agonist treatment or opioid agonist detoxification therapy
The flare-up regimens involve early follicular phase beginning of the GnRH agonist, with minimal delay before the onset of gonadotrophin administration (1, 2).
We calculated compound reproducibility for all NR assays in both agonist and antagonist mode using the ratio readout.
based Anchor Therapeutics announced the publication of new research that describes the identification and characterization of a pepducin-based allosteric agonist that targets CXCR4, a chemokinc G protein-coupled receptor (GPCR) found on hematopoietic stem cells and other bone marrow-derived cells.
Patients receiving a GnRH agonist should be monitored for the development of diabetes and cardiovascular disease, says the agency, adding that such cardiovascular risk factors as smoking and increases in blood pressure, cholesterol, blood sugar and weight should be managed according to current clinical practice.
Washington, May 11 (ANI): People who take dopamine agonist medications for Parkinson's disease tend to display traits of compulsive behaviour- like pathological gambling, compulsive shopping, binge eating and other impulse control disorders.