For nonsmokers who drank fewer than 30 drinks per week, the form of
alcohol dehydrogenase had no bearing on oral cancer risk, Peters reported on March 30 at the meeting of the American Association for Cancer Research in Orlando.
For the five B populations and the five O populations, gels were stained for
alcohol dehydrogenase, [Alpha]-glycerol-3-phosphate dehydrogenase, phosphoglucomutase, and CuZn-superoxide dismutase, among other enzymes (Pasteur et al.
It has recently been reported that
alcohol dehydrogenase (ADH) activity in gastric mucosa contributes substantially to the first-pass metabolism of ethanol[5], and that activities in the stomach are lower in women than in men[6].
Gene variants encoding several of the alcohol-metabolizing enzymes,
alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), are among the largest genetic associations with risk for alcohol dependence.
Alcohol dehydrogenase enzyme has a catalytic role in regeneration of acetaldehyde to ethanol.
The product is an
alcohol dehydrogenase inhibitor used for the treatment of ethylene glycol and methanol poisonings.
In the beginning the liver metabolises ethanol into acetaldehyde through an enzyme,
alcohol dehydrogenase (ADH), before breaking it into acetate by aldehyde dehydrogenase (ALDH).
Let's look again at Example 1, which shows the abstract for a study of a competitive inhibitor of
alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol.
haemodialysis) and inhibition of the metabolism of methanol to toxic formic acid by competitive inhibition of the enzyme
alcohol dehydrogenase (with ethyl alcohol or fomepizole).
Nearly all of the proteins altered in significant amounts were identified as enzymes associated with important metabolic pathways, such as
alcohol dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), Xaa-His dipeptidase, ornithine carbamoyltransferase, putative O-acetylserine lyase, enolase (2-phosphoglycerate dehydratase), fructose-bisphosphate aldolase, and cysteine synthase.
Much of this research has focused on polymorphisms in the genes encoding the enzyme
alcohol dehydrogenase (ADH), which catalyzes the oxidation of ethanol to acetaldehyde.
New research involving a polymorphism of
alcohol dehydrogenase may provide answers.
