The cellular reactions caused by chronic hyperglycemia are nonenzymatic glycation, activation of the signal transduction pathway increasing DAG synthesis, increased ROS synthesis as the waste product of energy catabolism leading to cell and tissue oxidative stress, and activation of aldolase
The three genetically known types of PH are PH1, which is caused by a mutation in the AGXT gene, causing a deficiency of the enzyme alanine: glyoxylate-aminotransferase, PH2, which is caused by a mutation in the GRHPR gene, causing a deficiency of the enzyme glyoxylate/hydroxypyruvate reductase (GR/HPR), and PH3, which is caused by a mutation in the HOGA1 gene, causing a deficiency of the enzyme 4-hydroxy-2-oxoglutarate aldolase
It was reported in goats that lithium-poor nutrition decreased feed intake in growing youngones, lower birth weight of kids, lesser conception rate, increased abortion rates, delivery of more female kids, decreased milk production, life expectancy and serum enzyme activity (isocitric acid dehydrogenase, malate dehydrogenase, aldolase
, and glutamine dehydrogenase), except stress indicator enzyme (creatinine kinase), and skin lesions (Anke et al., 1983, 1991; Mueller et al., 2010).
The monitoring RA treatment efficiency tests segment is also further divided into salicylate level count, muscle enzyme tests (CPK, Aldolase
) and creatinine test.
The presence of a positive aldolase
above the upper limit of normal) and increasing age were associated with worse survival, whereas high antinuclear antibody titers (1:1280 or higher) were associated with improved survival.
Muscle enzymes were elevated (creatinine kinases [CK] of 309 IU/L and aldolase
of 12.8 IU/L), and there was an increase in acute phase reactants, with an ESR of 34 mm/h, PCR of 4.09 mg/dL, and ferritin of 614 ng/mL There was also an increase in hepatic enzymes (GOT 694 IU/L, GPT 1044 IU/L, FA 130 IU/L).
Nitrite in processed meats can inhibit the growth of foodborne pathogens and food spoilage bacteria through various mechanisms, including oxygen uptake and oxidative phosphorylation interruption, formation of nitrous acid and NOs, and interruption of critical enzymes in bacterial metabolism such as aldolase
ICT is immunochromato-graphic capture assays with monoclonal anti-bodies to species-specific antigens (histidine-rich protein2 [PfHRP2]), aldolase
of plasmodium falciparum and conserved plasmodium antigens (lactate dehydrogenase).
Fructose 1,6-bisphosphate aldolase
(EC 18.104.22.168), usually known as aldolase
, is an enzyme that participates in glycolysis.
(4) Rhabdomyolysis is a clinical syndrome caused by damaged skeletal muscles and subsequent release of their intracellular components and breakdown products into the circulation, including myoglobin, creatine kinase, aldolase
, lactate dehydrogenase, and electrolytes.
It is known though that HNF4A regulates expression of genes involved in glucose transport (GLUT2), glycolysis (aldolase
B, liver pyruvate kinase), and lipid metabolism (Apo AII, apoB, and apoCIII) .
Bertinat et al., "Different involvement for aldolase
isoenzymes in kidney glucose metabolism: aldolase
B but not aldolase
A colocalizes and forms a complex with FBPase," Journal of Cellular Physiology, vol.