alopecia areata

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Related to alopecia areata: alopecia totalis, alopecia universalis
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Noun1.alopecia areata - patchy baldnessalopecia areata - patchy baldness      
alopecia - loss of hair (especially on the head) or loss of wool or feathers; in humans it can result from heredity or hormonal imbalance or certain diseases or drugs and treatments (chemotherapy for cancer)
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(NASDAQ: ACRS), a physician-led biopharmaceutical company focused on immuno-inflammatory and dermatological diseases, today announced results from its Phase 2 clinical trial of ATI-501 (AUAT-201 Oral), an investigational oral Janus Kinase (JAK) 1/3 inhibitor, in subjects with alopecia areata (AA).
[5] There are several publications reporting high dose pulse steroid treatment for alopecia areata. [6-9]
(NASDAQ: CNCE) has completed patient enrollment of an open label clinical trial to evaluate once-daily compared to twice-daily oral dosing of CTP-543 in patients with alopecia areata, the company said.
Studies show that in Alopecia areata, failure of this immune privilege results in type 1 cellular immunity mediated by cytotoxic T lymphocytes which attack hair follicles and prevent them from entering the growing phase of the hair cycle.3 These cytotoxic T lymphocytes depend on the Interleukin-15 pathway which utilizes Janus Kinase (JAK) proteins for downstream signaling.
United States-based Pfizer has commenced a phase 2b/3 clinical trial of PF-06651600, an oral JAK3 inhibitor, intended to treat patients with moderate to severe alopecia areata, it was reported on Friday.
Alopecia areata affects an estimated 75 million people worldwide on a chronic and recurring basis, including 37 million with alopecia totalis or universalis, according to Dr.
Keywords: Multiple autoimmune syndrome, lichen planus, vitiligo, alopecia areata, isotopic phenomenon.
Specifically, the analysis found, alopecia areata patients are at risk for any mental health disorder, anxiety disorders, attention-deficit/hyperactivity disorder, dementia, mood disorders, personality disorders, and suicide or intentionally self-inflicted injury.
In a previous study, the researchers identified a genetic signal, which is a gene called named IKZF1- in alopecia areata.
CHICAGO -- How do you talk to your alopecia areata patients and their families about hair loss?