alpha-adrenergic antagonist


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alpha-adrenergic antagonist

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In addition, "emerging, exciting evidence" supports the use of the alpha-adrenergic antagonist prazosin for alleviating nightmares and sleep disruptions associated with the disorder, said Dr.
Phentolamine mesylate, chemical formula C17H19N30-CH4S03, is a nonselective alpha-adrenergic antagonist.(5) It acts as a competitive inhibitor, blocking the effects of epinephrine, an active ingredient in some local anesthetics that causes vasoconstriction.(3,6) As an alpha-adrenergic blocking agent, phentolamine's main effect is vasodilation of the blood vessels.
Optimal medical management such as starting patients on alpha-adrenergic antagonists weeks prior to any elective procedure and discussing with the patient perioperative complications and risks are essential.