alpha-blocker


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al·pha-block·er

(ăl′fə-blŏk′ər)
n.
A drug that blocks or counteracts the effects of epinephrine and other molecules that stimulate alpha-receptors, leading to various physiological reactions such as vasodilation and a decrease in blood pressure. Also called alpha-adrenergic antagonist, alpha-adrenergic blocker.

alpha-blocker

n
(Pharmacology) any of a class of drugs that prevent the stimulation of alpha adrenoceptors, a type of receptor in the sympathetic nervous system, by adrenaline and noradrenaline and that therefore cause widening of blood vessels: used in the treatment of high blood pressure and prostatic hyperplasia
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.alpha-blocker - any of various drugs that block alpha-adrenergic receptorsalpha-blocker - any of various drugs that block alpha-adrenergic receptors; used in treating benign prostatic hyperplasia; relaxes the muscles of the prostate and bladder
blocking agent, blocker - a class of drugs that inhibit (block) some biological process
Minipress, prazosin - antihypertensive drug (trade name Minipress)
Hytrin, terazosin - antihypertensive drug (trade name Hytrin) used to treat high blood pressure
References in periodicals archive ?
Researchers reviewed data from two cohorts (one from the U.K., another from Taiwan) involving a total of nearly 147,000 men treated with 5-ARIs--finasteride (Proscar[R]) or dutasteride (Avodart[R])--or the selective alpha-blocker tamsulosin (Flomax[R]).
We included six studies with 335 participants (alpha-blocker 185, placebo with/without analgesics 150) in the analysis for SFR [21, 22, 23-25, 27].
ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) linked the alpha-blocker doxazosin (Cardura) to an increased risk of heart failure and stroke, which led to the early cessation of the doxazosin arm.
Selective alpha-blockers are commonly used, as the nonselective alpha-blocker phenoxybenzamine, which remains the gold standard, is not easily accessible in Canada.
Drug class listed Drug name in publication Actual drug class Apraclonidine Adrenergic agonist [Alpha.sub.2]-agonist Brimonidine (ophthalmic) Adrenergic agonist [Alpha.sub.2]-agonist; antiglaucoma Dapiprazole Miotic Alpha-blocker Dipivefrine Prostaglandin Prodrug of epinephrine Naphazoline (ophthalmic) Decongestant [Alpha.sub.1]-agonist; vasoconstrictor; imidazoline derivative Tetryzoline (ophthalmic) Decongestant Adrenergic agonist; vasoconstrictor; imidazoline derivative
Safety and tolerability of solifenacin add-on therapy to alpha-blocker treated men with residual urgency and frequency.
Loop diuretics, thiazide diuretics, angiotensin receptor blocker, beta-blocker, and alpha-blocker were not associated with the risk of NOF.
Use of anti-hypertensive drugs such as selective beta blocker, alpha-blocker, CCB and/or other combinations more commonly used in non-diabetic than in diabetics.
Along with type II 5-alpha-reductase inhibitors and anti-cholinergics, alpha-blocker medications are frequently used in urology for the treatment of LUTS and benign prostatic hyperplasia.
Material and methods: In our study, we included one hundred patients with LUTS who did not receive any medical treatment, and one hundred patients with LUTS who did not respond to alpha-blocker drugs other than doxazosin XL (8 mg).
Alpha-blocker medications can relax the smooth muscles in the bladder neck and prostate to improve urine flow.
Labetalol is both a selective alpha-blocker and a nonselective beta-blocker that decreases systemic vascular resistance without changing maternal cardiac output.