alpha-fetoprotein


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Related to alpha-fetoprotein: carcinoembryonic antigen, Alpha-Fetoprotein Test

al·pha-fe·to·pro·tein

 (ăl′fə-fē′tō-prō′tēn, -tē-ĭn)
n. Abbr. AFP
A glycoprotein that is abundant in the blood plasma of human and other mammalian fetuses and is also present in the serum of people with certain diseases, such as liver cancer. Abnormal levels in maternal serum are associated with certain fetal abnormalities, including Down syndrome and spina bifida.

alpha-fetoprotein

(ˌælfəˌfiːtəʊˈprəʊtiːn)
n
(Biochemistry) a protein that forms in the liver of the human fetus. Excessive quantities in the amniotic fluid and maternal blood may indicate spina bifida in the fetus; low levels may point to Down's syndrome. Abbreviation: afp

al`pha-fe`to•pro′tein

(ˌfi toʊˈproʊ tin, -ti ɪn)

n.
a serum protein produced during pregnancy, useful in the prenatal diagnosis of multiple births or birth defects. Abbr.: AFP
[1970–75]
References in periodicals archive ?
"While there have been some recent advances, there are still limited treatment options for people with this type of cancer and--until now--there was no treatment option specifically indicated for patients with increased alpha-fetoprotein concentrations.
Carbohydrate structures of human alpha-fetoprotein of patients with hepatocellular carcinoma: presence of fucosylated and non-fucosylatedtriantennaryglycans.
Xu et al., "Clinicopathological characteristics and prognosis of alpha-fetoprotein positive gastric cancer in Chinese patients," International Journal of Clinical and Experimental Pathology, vol.
Dalhoff, "Alpha-fetoprotein is a predictor of outcome in acetaminophen-induced liver injury," Hepatology, vol.
Matsumoto et al., "Clinicopathological features of alpha-fetoprotein producing early gastric cancer with enteroblastic differentiation," World Journal of Gastroenterology, vol.
Maternal serum alpha-fetoprotein measurement: a screening test for Down syndrome.
Hereditary persistence of alpha-fetoprotein (HPAF P): review of the literature.
In the setting of a pediatric testis mass with a normal alpha-fetoprotein (AFP), an attempt at testis-sparing surgery is not oncological heresy.
Laboratory investigations demonstrated an elevated alpha-fetoprotein blood level (204.0 nanograms per milliliter) and aspartate transaminase (304IU per liter), slightly normal alanine transaminase (40.8 IU per liter), positive hepatitis B surface antigen, a normochromic normocytic anemia (10 grams per deciliter), and low serum albumin level (32 grams per liter).
Considering amniocentesis for alpha-fetoprotein and acetyl cholinesterase
Further blood tests were done and the most notable findings were as follows: alpha-fetoprotein 10 148 pg/L; beta-human chorionic gonadotrophin 236 IU/L; alkaline phosphatase 369 U/L; gamma-glutamyl transferase 514 U/L; and aspartate transaminase 283 U/L.