macrophage

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mac·ro·phage

 (măk′rə-fāj′)
n.
Any of various large, phagocytic white blood cells that develop from monocytes, are found in the spleen, liver, and other tissues, and have a variety of functions in the immune system including engulfing and destroying pathogens and dead cells, presenting antigens to activate lymphocytes, and releasing cytokines that mediate inflammation.


mac′ro·phag′ic (-făj′ĭk) adj.

macrophage

(ˈmækrəʊˌfeɪdʒ)
n
(Zoology) any large phagocytic cell occurring in the blood, lymph, and connective tissue of vertebrates. See also histiocyte
macrophagic adj

mac•ro•phage

(ˈmæk rəˌfeɪdʒ)

n.
a large white blood cell, occurring principally in connective tissue and in the bloodstream, that ingests foreign particles and infectious microorganisms by phagocytosis.
[< German Makrophagen (pl.) (Metchnikoff, 1887), with -phagen representing Phagozyten phagocytes; see macro-, -phage]
mac`ro•phag′ic (-ˈfædʒ ɪk) adj.

mac·ro·phage

(măk′rə-fāj′)
Any of the large white blood cells in many vertebrates that engulf and break down foreign particles and bacteria in blood or lymph. Macrophages are important in the body's defense against disease and are found mainly in the spleen, lymph nodes, and liver.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.macrophage - a large phagocytemacrophage - a large phagocyte; some are fixed and other circulate in the blood stream
histiocyte - a macrophage that is found in connective tissue
phagocyte, scavenger cell - a cell that engulfs and digests debris and invading microorganisms
Translations
makrofág
FresszelleMakrophage
マクロファージ
makrofag

mac·ro·phage

n. macrófago, célula mononuclear fagocítica;
___ migrationmigración de ___ -s.
References in periodicals archive ?
Similarly interstitial fibrosis and thickening, lymphocytic and plasmacytic infiltrates and accumulation of intra alveolar macrophage and giant cells were detected in histopathologic examination of our patient.
HMGB1, TLR4, and p-NF-[kappa]B expression in LPS-stimulated alveolar macrophage cells
Aaron Scott, Ph.D., from the University of Birmingham in the United Kingdom, and colleagues compared the effect of unvaped ECL to ECVC on alveolar macrophage function.
Allen et al., "Challenges for inhaled drug discovery and development: induced alveolar macrophage responses," Advanced Drug Delivery Reviews, vol.
Mancuso, "Cigarette smoke exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of Streptococcus pneumoniae," Infection and Immunity, vol.
AM: Alveolar macrophage ATAC: Assay for transposase-accessible chromatin COPD: Chronic obstructive pulmonary disease ChIP: Chromatin immunoprecipitation DC: Dendritic cell ECM: Extracellular matrix GSH: Glutathione HO-1: Heme oxygenase 1 IM: Interstitial macrophage MMP: Metalloproteinase NE: Neutrophil elastase PRR: Pathogen recognition receptor ROS: Reactive oxygen species.
Although there are no previous reports linking alcohol abuse to PAP, alcohol has been demonstrated to inhibit alveolar macrophage function in animal and molecular models.
The mechanisms responsible for rendering people with alcohol use disorder (AUD) vulnerable to lung damage include alterations in host defenses of the upper and lower airways, disruption of alveolar epithelial barrier integrity, and alveolar macrophage immune dysfunction.
Bowden, "Chemotactic and mitogenic components of the alveolar macrophage response to particles and neutrophil chemoattractant," The American Journal of Pathology, vol.
Animal studies have shown that inhalational exposure to nanoparticles can lead to emphysema, alveolar macrophage aggregation, diffuse alveolar damage, proliferation of type II alveolar epithelial cells, and epithelial apoptosis in rats [6].