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A drug, C10H17, used in its hydrochloride form as an antiviral agent and treatment for Parkinson's disease.

[Alteration of adamantane, a hydrocarbon + -ine.]


(Pharmacology) an antiviral drug used in the treatment of some types of influenza and to reduce some of the symptoms of Parkinson's disease
[C20: a blend of amine + adamantane the chemical compound from which it is derived]


(əˈmæn təˌdin)

a water-soluble crystalline substance, C10H17NHCl, that inhibits penetration of viruses into cells and is used against certain types of influenza and in the treatment of parkinsonism.
[1960–65; coinage appar. based on the chemical name 1-aminoadamantane]


n amantadina
References in periodicals archive ?
It was de-branded last October and is now sold as amantadine.
Additionally, Bioo Scientific will present optimized immunoaffinity columns for mycotoxin analysis, and a solution for high-throughput detection of amantadine residues in poultry.
Constantly evolving viral genome induces resistance against current anti- influenza drug regimens comprising newly developed drugs such Tamiflu, zanamivir, amantadine, etc.
Nevertheless, competition from clinical mainstays will make it difficult for late entrants like Newron/Zambon/Meiji Seika Pharma's monoamine oxidase B inhibitor safinamide, Bial/Ono's catechol-O-methyltransferase inhibitor opicapone, and Adamas' extended-release amantadine formulation Nurelin to garner a substantial share of the market unless significant clinical differentiation can be shown.
Asparagine was identified at position 31 of M2, which is the same in M2 of A/ duck/Korea/Buan2/2014 (H5N8) and confers resistance to amantadine and rimantadine (10).
Both M2-ion channel blockers, such as amantadine, and neuraminidase inhibitors, such as Tamiflu or Relenza, are used as antiviral drugs for influenza infections of humans," Richt said.
If started promptly, antiviral medications may reduce complications of acute influenza, but increasing resistance to amantadine and perhaps neuraminidase inhibitors underscores the need for novel prevention and treatment strategies.
According to World Health Organization guidelines published in 2007, "modified regimens of oseltamivir treatment, including twofold higher dosage, longer duration, and, possibly, combination therapy with amantadine or rimantadine (in countries where A(H5N1) viruses are likely to be susceptible to aman-tadines), may be considered on a case by case basis, especially in patients with pneumonia or progressive disease.
Le traitement consiste a prendre le medicament viral de base "le Tami flu" ou un des traitements antiviraux qui ne peuvent etre pris que sur ordre du medecin: Oseltamivir; Zanamivir; Amantadine et le Ramantadine.
An analysis of its genes also found that the virus can be treated by amantadine, a common antiviral drug.
He had been suffering from Parkinson's disease for nine years, and his long-term anti-Parkinson's treatment was levodopa 250 mg/carbidopa 25 mg (Sinemet[R], Merck Sharp and Dohme (Australia) Pty Ltd, Sydney, NSW) five times per day and amantadine (Novartis Pharmaceuticals Australia Pty Limited, Sydney, NSW) 100 mg twice a day.
Clinical trials have documented that amantadine hydrochloride [4,5,7,8,13] and its analog rimantadine hydrochloride [3,5,10,13,15] are effective drugs for the prophylaxis and treatment of influenza A virus infection.