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Total loss of vision, especially when occurring without pathological changes to the eye.

[Greek amaurōsis, from amauroun, to make dim, from amauros, dark.]

am′au·rot′ic (-rŏt′ĭk) adj.


(Medicine) pathol blindness, esp when occurring without observable damage to the eye
[C17: via New Latin from Greek: darkening, from amauroun to dim, darken]
amaurotic adj


(ˌæm ɔˈroʊ sɪs)

partial or total loss of sight, esp. in the absence of a gross lesion or injury.
[1650–60; < Greek: darkening, hindrance to sight]
am`au•rot′ic (-ˈrɒt ɪk) adj.


a condition of partial or total blindness, caused by a disease of the optie nerve. — amaurotic, adj.
See also: Blindness
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.amaurosis - partial or total loss of sight without pathology of the eyeamaurosis - partial or total loss of sight without pathology of the eye; caused by disease of optic nerve or retina or brain
vision defect, visual defect, visual disorder, visual impairment - impairment of the sense of sight
References in periodicals archive ?
The lead program in the ophthalmology pipeline, QR-110, is currently in a Phase 1/2 safety and efficacy trial in adult and pediatric patients with Leber's congenital amaurosis 10, due to the p.
Recently, validation and expansion of the platform included positive results in clinical trials in cystic fibrosis and initiating a clinical trial in Leber's congenital amaurosis.
winnerRenee Dooley RENEE Dooley, from Thorntree, was diagnosed with leber congenital amaurosis - a rare condition that will eventually cause her to lose her sight.
Screening of SPATA7 in patients with Leber congenital amaurosis and severe childhood-onset retinal dystrophy reveals disease-causing mutations.
Background: Leber congenital amaurosis (LCA) is a visual disease which is caused by RPE65 mutations and results in retinal degeneration and severe vision loss in early infancy.
EDIT-101 for Leber Congenital Amaurosis type 10 (LCA10) remains on track for a mid-2018 IND filing
Gene Therapy to Activate RPE65 for Leber Congenital Amaurosis - Drug Profile 75
I was born with Leber congenital amaurosis, a genetic condition that means that I have very little useful vision.
Contralateral Amaurosis After Retrobulbar Block For Vitrectomy Presenting Solely with Hypertension and Tachycardia.
JS plus retinopathy, primary criteria and retinal abnormality (congenital leber amaurosis, pigmentary retinopathy, or unspecific retinitis).
Hemispheric neurological symptoms, amaurosis fugax, and Hollenhorst plaques detected in ophthalmologic examination are findings that require imaging in the diagnosis of CAS.
Experts told his mother that his eyesight will get worse through the years, Guardino was diagnosed with Leber congenital amaurosis.