Cementoblastoma, osteoid osteoma, cemento-osseous lesions, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, and
ameloblastic fibro-odontoma were also considered in the differential diagnoses.
In our study majority of cases were of Squamous cell carcinoma constituting 67.9% cases, Haemangioma 5.8% cases, chronic tonsillitis 4.8% cases, chronic inflammation 1.9% cases, squamous papilloma 2.9% cases, verrucous carcinoma, fibrolipoma,
ameloblastic carcinoma, epulis and lichen planus constituting 1.9% cases each respectively and pleomorphic adenoma, adenoid cystic carcinoma, lymphangioma, basal cell carcinoma, angiofibroma, fibrous histiocytoma and NHL constituting 0.9% cases each respectively.
This especially applies to
ameloblastic carcinoma, where there may be varying degrees of cytologic atypia (Figure 1).
A differential diagnosis is also possible where DCs can be distinguished from odontogenic keratocyst,
ameloblastic fibroodontoma,
ameloblastic fibroma, calcifying epithelial odontogenic tumor, adenomatoid odontogenic tumor, and unicystic ameloblastoma (7).
It became
ameloblastic carcinoma in 2016 and he had the first of several operations that August.
(1) Although there is controversy regarding the true nature of POT as a newly-recognized embryonal neoplasm of immature dental tissue exhibiting progressive growth potential or just a histopathological variant of
ameloblastic fibroma, or odontogenic myxoma/fibroma.
[1] also compared CD138 expression in
ameloblastic carcinomas, peripheral ameloblastomas, and desmoplastic ameloblastomas, and they found the greater loss of this component in
ameloblastic carcinoma.
The diagnosis of PIOSCC can be difficult, and it must be differentiated from other malignancies such as
ameloblastic carcinoma and metastatic carcinomas; when it causes destruction of the cortical bone and invades adjacent soft tissues, it may be confused with a carcinoma of the oral mucosa.
Birn, "The adenomatoid odontogenic tumour,
ameloblastic adenomatoid tumour or adenoameloblastoma," APMIS-Acta Pathologica, Microbiologica et Immunologica Scandinavica, vol.
COC may be associated with other odontogenic lesions, especially to odontomas (ranging from 22% to 47%), ameloblastomas, adenomatoid odontogenic tumors, and
ameloblastic fibromas [15].
Unicystic ameloblastoma is a cystic lesion that shows clinical and radiographic features that resemble those of odontogenic cysts, though histological features are crucial to ascertain the presence of
ameloblastic epithelium and its variants [1].
It is characterized by secreting a unique amyloid protein which is called 'odontogenic
ameloblastic associated protein' (19) which often calcifies.
ameloblast - a cell from which tooth enamel develops